ID   DIB1_ASHGO              Reviewed;         143 AA.
AC   Q75BD8;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Spliceosomal protein DIB1;
GN   Name=DIB1; OrderedLocusNames=ADL374W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Essential role in pre-mRNA splicing. Also essential for entry
CC       into mitosis (G2/M progression) as well as for chromosome segregation
CC       during mitosis (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the 25S [U4/U6.U5] tri-snRNP. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DIM1 family. {ECO:0000305}.
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DR   EMBL; AE016817; AAS51546.1; -; Genomic_DNA.
DR   RefSeq; NP_983722.1; NM_209075.1.
DR   AlphaFoldDB; Q75BD8; -.
DR   SMR; Q75BD8; -.
DR   STRING; 33169.AAS51546; -.
DR   EnsemblFungi; AAS51546; AAS51546; AGOS_ADL374W.
DR   GeneID; 4619857; -.
DR   KEGG; ago:AGOS_ADL374W; -.
DR   eggNOG; KOG3414; Eukaryota.
DR   HOGENOM; CLU_117348_0_0_1; -.
DR   InParanoid; Q75BD8; -.
DR   OMA; DFNEMYE; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IBA:GO_Central.
DR   GO; GO:0005682; C:U5 snRNP; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:EnsemblFungi.
DR   CDD; cd02954; DIM1; 1.
DR   InterPro; IPR004123; Dim1.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR12052; PTHR12052; 1.
DR   Pfam; PF02966; DIM1; 1.
DR   PIRSF; PIRSF017199; mRNA_splic_U5; 1.
DR   SMART; SM01410; DIM1; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Mitosis; mRNA processing; mRNA splicing;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..143
FT                   /note="Spliceosomal protein DIB1"
FT                   /id="PRO_0000218283"
SQ   SEQUENCE   143 AA;  16724 MW;  3D4D6094337D1D66 CRC64;
     MGSVFLPHLH SGWHVDQAIV TEEERLVVIR FGSDSDRSCM LMDEILYSIA EKVVNFAAIY
     VCDTTEVPDF NEMYELQDPM TVMFFYKNKH MRCDFGTGNN NKMNFVVDNK QEMIDIIETV
     FRGARRNKGL VVSPYDYNYK RIQ