ID   DICB_ECOLI              Reviewed;          62 AA.
AC   P09557; P77571;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 3.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=Division inhibition protein DicB;
GN   Name=dicB; OrderedLocusNames=b1575, JW1566;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3041373; DOI=10.1093/nar/16.14.6327;
RA   Cam K., Bejar S., Gil D., Bouche J.-P.;
RT   "Identification and sequence of gene dicB: translation of the division
RT   inhibitor from an in-phase internal start.";
RL   Nucleic Acids Res. 16:6327-6338(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA   Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA   Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA   Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA   Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA   Wada C., Yamamoto Y., Horiuchi T.;
RT   "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 28.0-40.1 min region on the linkage map.";
RL   DNA Res. 3:363-377(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   NEUTRALIZED BY CBEA.
RC   STRAIN=K12 / BW25113;
RX   PubMed=22515815; DOI=10.1111/j.1365-2958.2012.08068.x;
RA   Masuda H., Tan Q., Awano N., Wu K.P., Inouye M.;
RT   "YeeU enhances the bundling of cytoskeletal polymers of MreB and FtsZ,
RT   antagonizing the CbtA (YeeV) toxicity in Escherichia coli.";
RL   Mol. Microbiol. 84:979-989(2012).
CC   -!- FUNCTION: Involved in cell division inhibition; this function can be
CC       repressed by DicA and DicC proteins as well as antitoxin CbeA (yeeU).
CC       {ECO:0000269|PubMed:22515815}.
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DR   EMBL; X07465; CAA30351.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC74647.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15279.1; -; Genomic_DNA.
DR   PIR; A64913; CEECDB.
DR   RefSeq; NP_416092.1; NC_000913.3.
DR   RefSeq; WP_000854559.1; NZ_STEB01000003.1.
DR   AlphaFoldDB; P09557; -.
DR   BioGRID; 4261062; 85.
DR   BioGRID; 850470; 4.
DR   DIP; DIP-9440N; -.
DR   IntAct; P09557; 6.
DR   STRING; 511145.b1575; -.
DR   PaxDb; P09557; -.
DR   PRIDE; P09557; -.
DR   EnsemblBacteria; AAC74647; AAC74647; b1575.
DR   EnsemblBacteria; BAA15279; BAA15279; BAA15279.
DR   GeneID; 67415721; -.
DR   GeneID; 946110; -.
DR   KEGG; ecj:JW1566; -.
DR   KEGG; eco:b1575; -.
DR   PATRIC; fig|1411691.4.peg.687; -.
DR   EchoBASE; EB0223; -.
DR   eggNOG; ENOG5031KUY; Bacteria.
DR   HOGENOM; CLU_208424_0_0_6; -.
DR   OMA; NQICIVS; -.
DR   BioCyc; EcoCyc:EG10227-MON; -.
DR   PRO; PR:P09557; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0051782; P:negative regulation of cell division; IDA:EcoCyc.
DR   GO; GO:0051302; P:regulation of cell division; IMP:EcoliWiki.
DR   InterPro; IPR008022; DicB.
DR   Pfam; PF05358; DicB; 1.
PE   4: Predicted;
KW   Cell cycle; Cell division; Reference proteome.
FT   CHAIN           1..62
FT                   /note="Division inhibition protein DicB"
FT                   /id="PRO_0000079895"
FT   CONFLICT        39
FT                   /note="E -> Q (in Ref. 1; CAA30351)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   62 AA;  6964 MW;  3BD2A7DAD42831F2 CRC64;
     MKTLLPNVNT SEGCFEIGVT ISNPVFTEDA INKRKQEREL LNKICIVSML ARLRLMPKGC
     AQ