ID   DICH_ANTMA              Reviewed;         314 AA.
AC   Q9SNW8;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Transcription factor DICHOTOMA;
GN   Name=DICH;
OS   Antirrhinum majus (Garden snapdragon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Plantaginaceae; Antirrhineae; Antirrhinum.
OX   NCBI_TaxID=4151;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], DEVELOPMENTAL STAGE, FUNCTION, AND DISRUPTION
RP   PHENOTYPE.
RX   PubMed=10571179; DOI=10.1016/s0092-8674(00)81523-8;
RA   Luo D., Carpenter R., Copsey L., Vincent C., Clark J., Coen E.;
RT   "Control of organ asymmetry in flowers of Antirrhinum.";
RL   Cell 99:367-376(1999).
CC   -!- FUNCTION: Transcription regulator involved in the dorsovental asymmetry
CC       of flowers. Promotes dorsal identity. {ECO:0000269|PubMed:10571179}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00701}.
CC   -!- DEVELOPMENTAL STAGE: First observed in a dorsal domain of floral
CC       meristems, prior to any morphological dorsoventral asymmetry. Later,
CC       expression becomes restricted to the most dorsal half of each dorsal
CC       petals. {ECO:0000269|PubMed:10571179}.
CC   -!- DISRUPTION PHENOTYPE: Petals are more symmetrical than in the wild
CC       type. {ECO:0000269|PubMed:10571179}.
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DR   EMBL; AF199465; AAF12817.1; -; mRNA.
DR   AlphaFoldDB; Q9SNW8; -.
DR   SMR; Q9SNW8; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0048262; P:determination of dorsal/ventral asymmetry; IMP:UniProtKB.
DR   GO; GO:0009908; P:flower development; IMP:UniProtKB.
DR   InterPro; IPR017888; CYC/TB1_R_domain.
DR   InterPro; IPR017887; TF_TCP_subgr.
DR   InterPro; IPR005333; Transcription_factor_TCP.
DR   PANTHER; PTHR31072; PTHR31072; 1.
DR   Pfam; PF03634; TCP; 1.
DR   PROSITE; PS51370; R; 1.
DR   PROSITE; PS51369; TCP; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Nucleus; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..314
FT                   /note="Transcription factor DICHOTOMA"
FT                   /id="PRO_0000419438"
FT   DOMAIN          87..145
FT                   /note="TCP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00701"
FT   DOMAIN          201..218
FT                   /note="R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00702"
SQ   SEQUENCE   314 AA;  35567 MW;  7DC0849B480A0DCF CRC64;
     MFNKKRYLQY PQVPPSLNPR ASTSVVSLNG NEILLHHHDV ISGYYLASNP QNLEPDALFN
     GFHHDVGGTN GDPLVLANTL AKKHTPKKDR HSKINRPQGP RDRRVRLSIG IARKFFDLQE
     MLGFDKPSKT LDWLLTKSKE AIKELVQSKS SKSNISNSPS ECDQEVLSAD LPYIGSSKGK
     AAVGLNSNKC KGGRDAVDLA KESRAKARAR ARERTKEKMC IKQLNQERNK SYEWNPSVLF
     QSKSSQQFEV SGPSTNYEEL NQESIMIKRK LKQNHPSMFG FQPENATENW DYYSNFTSQS
     NQLCAILDQH KFIN