DICT_DICLA
ID DICT_DICLA Reviewed; 79 AA.
AC P59906;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 10-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 39.
DE RecName: Full=Dicentracin;
DE AltName: Full=Dicentracine;
DE Flags: Precursor;
OS Dicentrarchus labrax (European seabass) (Morone labrax).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Moronidae; Dicentrarchus.
OX NCBI_TaxID=13489;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Salerno G., Roch P., Sri Widada J.;
RT "Dicentracine, first antimicrobial peptide isolated from the fish
RT Dicentrarchus labrax.";
RL Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the pleurocidin family. {ECO:0000305}.
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DR EMBL; AY303949; AAP58960.1; -; mRNA.
DR AlphaFoldDB; P59906; -.
DR SMR; P59906; -.
DR Proteomes; UP000694389; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR InterPro; IPR012515; Antimicrobial12.
DR Pfam; PF08107; Antimicrobial12; 1.
PE 3: Inferred from homology;
KW Amidation; Antibiotic; Antimicrobial; Reference proteome; Secreted; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT PEPTIDE 23..44
FT /note="Dicentracin"
FT /id="PRO_0000000281"
FT PROPEP 47..79
FT /evidence="ECO:0000250"
FT /id="PRO_0000000282"
FT REGION 48..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 44
FT /note="Glycine amide"
FT /evidence="ECO:0000250"
SQ SEQUENCE 79 AA; 9152 MW; CB23E3270E5B4AFE CRC64;
MKCATLFLVL SMVVLMAEPG DAFFHHIFRG IVHVGKSIHK LVTGGKAQQD QQDQQYQQDQ
QDQQAEQYQR FNRERAAFD