ID   ADC1_BRADU              Reviewed;         250 AA.
AC   Q89CN4;
DT   01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Acetoacetate decarboxylase 1 {ECO:0000255|HAMAP-Rule:MF_00597};
DE            Short=AAD 1 {ECO:0000255|HAMAP-Rule:MF_00597};
DE            Short=ADC 1 {ECO:0000255|HAMAP-Rule:MF_00597};
DE            EC=4.1.1.4 {ECO:0000255|HAMAP-Rule:MF_00597};
GN   Name=adc1 {ECO:0000255|HAMAP-Rule:MF_00597}; OrderedLocusNames=bll7763;
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=224911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110;
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- FUNCTION: Catalyzes the conversion of acetoacetate to acetone and
CC       carbon dioxide. {ECO:0000255|HAMAP-Rule:MF_00597}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetoacetate + H(+) = acetone + CO2; Xref=Rhea:RHEA:19729,
CC         ChEBI:CHEBI:13705, ChEBI:CHEBI:15347, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526; EC=4.1.1.4; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_00597};
CC   -!- SIMILARITY: Belongs to the ADC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00597}.
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DR   EMBL; BA000040; BAC53028.1; -; Genomic_DNA.
DR   RefSeq; NP_774403.1; NC_004463.1.
DR   AlphaFoldDB; Q89CN4; -.
DR   SMR; Q89CN4; -.
DR   STRING; 224911.27356047; -.
DR   EnsemblBacteria; BAC53028; BAC53028; BAC53028.
DR   KEGG; bja:bll7763; -.
DR   PATRIC; fig|224911.5.peg.7984; -.
DR   eggNOG; COG4689; Bacteria.
DR   HOGENOM; CLU_077089_0_0_5; -.
DR   InParanoid; Q89CN4; -.
DR   OMA; YEWIKMP; -.
DR   PhylomeDB; Q89CN4; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0047602; F:acetoacetate decarboxylase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.400.10; -; 1.
DR   HAMAP; MF_00597; ADC; 1.
DR   InterPro; IPR010451; Acetoacetate_decarboxylase.
DR   InterPro; IPR023653; Acetoacetate_decarboxylase_bac.
DR   InterPro; IPR023375; ADC_dom_sf.
DR   Pfam; PF06314; ADC; 1.
DR   SUPFAM; SSF160104; SSF160104; 1.
PE   3: Inferred from homology;
KW   Decarboxylase; Lyase; Reference proteome; Schiff base.
FT   CHAIN           1..250
FT                   /note="Acetoacetate decarboxylase 1"
FT                   /id="PRO_0000207099"
FT   ACT_SITE        120
FT                   /note="Schiff-base intermediate with acetoacetate"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00597"
SQ   SEQUENCE   250 AA;  27823 MW;  431C505641C35145 CRC64;
     MGPPMKIEDV RRTAYSMPLT NPAFPPGPYR FFDREYFIIT YRTDPEALAT IVPEPLEVAE
     PLVKYEFIRM PDSTGFGDYT ETGQVIPVRF KGEEGGYTHA MYLDDEAPIA GGRELWGFPK
     KLARPKIEVE SDVLVGSLHY GSVLCASATM GYKHHKVDHD TVLKSMASPN FILKIIPHVD
     GSPRICELVR FHLDDVVLKE AWTGPAALGL FPHALCDVAR LPVREVISAL HFKADLTLGL
     GSVAFDYMAK