位置:首页 > 蛋白库 > DIML_CAEEL
DIML_CAEEL
ID   DIML_CAEEL              Reviewed;         525 AA.
AC   O17397;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Diminuto-like protein;
GN   ORFNames=F52H2.6;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SIMILARITY: Belongs to the DIMINUTO family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FO081446; CCD71661.1; -; Genomic_DNA.
DR   PIR; T32481; T32481.
DR   RefSeq; NP_508463.1; NM_076062.3.
DR   AlphaFoldDB; O17397; -.
DR   STRING; 6239.F52H2.6; -.
DR   EPD; O17397; -.
DR   PaxDb; O17397; -.
DR   PeptideAtlas; O17397; -.
DR   EnsemblMetazoa; F52H2.6a.1; F52H2.6a.1; WBGene00018718.
DR   GeneID; 186134; -.
DR   UCSC; F52H2.6; c. elegans.
DR   CTD; 186134; -.
DR   WormBase; F52H2.6; CE10874; WBGene00018718; -.
DR   eggNOG; KOG1262; Eukaryota.
DR   GeneTree; ENSGT00390000008338; -.
DR   HOGENOM; CLU_025883_4_0_1; -.
DR   InParanoid; O17397; -.
DR   OMA; YIPSRHY; -.
DR   OrthoDB; 733611at2759; -.
DR   PhylomeDB; O17397; -.
DR   Reactome; R-CEL-191273; Cholesterol biosynthesis.
DR   Reactome; R-CEL-6807047; Cholesterol biosynthesis via desmosterol.
DR   Reactome; R-CEL-6807062; Cholesterol biosynthesis via lathosterol.
DR   PRO; PR:O17397; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00018718; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR   ExpressionAtlas; O17397; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0000246; F:delta24(24-1) sterol reductase activity; IBA:GO_Central.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR   GO; GO:0008202; P:steroid metabolic process; IBA:GO_Central.
DR   Gene3D; 3.30.465.10; -; 1.
DR   InterPro; IPR040165; Diminuto-like.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   PANTHER; PTHR10801; PTHR10801; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   SUPFAM; SSF56176; SSF56176; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..525
FT                   /note="Diminuto-like protein"
FT                   /id="PRO_0000219497"
FT   DOMAIN          47..239
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00718"
SQ   SEQUENCE   525 AA;  61421 MW;  F4D567CCE2825928 CRC64;
     MNLVDEKDEK PTRWEKCVEF IMFHFRWVFV VPFLLPLSFL FNTVFDFRNR IVHAVNSAPN
     AHVRKVKHIQ EQLKEWNDNG RKSKLVNARP GWLTMSFRFP LYKENATKIA TDKLFDILDL
     DVEKMTVKAE PGVTMGQLSQ YLISRGYTLP VLPELDDLTV GGLINGCGVE SGSFKYGMFQ
     HICTGYEVVM SDGELKNVYP DSAAKTEQAK QDNSLFFAIP WSQGTICFLV AATIKIIPCK
     KYVKLTYKKT ETLSEMCEQL TEDSDRNSEN VDFVEALMFN KEKGCIMLGE FSDGPDTHDE
     VVNPIGRWYK KWFYTHVEDL INKKHESIEY IPLRDYYHRH SKSIFWELRD IVPFGNNVLF
     RYLMAWMCPP KIAFLKATTP NVLRKLYDRS HVLQDMLVPL DKLEECIDLF HKEVEIYPMW
     LCPFYLKSQP GLMKLRNATH KMYVDVGAYG VTSKDGYHHE RTTRRLESFV RSVNGFQMTY
     ADIYMTRAEY AEMFDRTLYD WKRASCKCID AFPDIYDKIC RSGRR
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024