ID   DIND_ECOLI              Reviewed;         274 AA.
AC   P23840; P76719; Q2M7V8;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=DNA damage-inducible protein D;
GN   Name=dinD; Synonyms=pcsA, yicD; OrderedLocusNames=b3645, JW3620;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=2664418; DOI=10.1111/j.1365-2958.1989.tb00184.x;
RA   Poulsen P., Andersen J.T., Jensen K.F.;
RT   "Molecular and mutational analysis of three genes preceding pyrE on the
RT   Escherichia coli chromosome.";
RL   Mol. Microbiol. 3:393-404(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=7686882; DOI=10.1006/geno.1993.1230;
RA   Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.;
RT   "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome:
RT   organizational symmetry around the origin of replication.";
RL   Genomics 16:551-561(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 137-167.
RX   PubMed=2158980; DOI=10.1128/jb.172.5.2774-2778.1990;
RA   Kubo K.M., Craig N.L.;
RT   "Bacterial transposon Tn7 utilizes two different classes of target sites.";
RL   J. Bacteriol. 172:2774-2778(1990).
RN   [6]
RP   IMPORTANCE AT HIGH TEMPERATURE.
RX   PubMed=1925027; DOI=10.1016/0923-2508(91)90042-9;
RA   Poulsen P., Jensen K.F.;
RT   "Three genes preceding pyrE on the Escherichia coli chromosome are
RT   essential for survival and normal cell morphology in stationary culture and
RT   at high temperature.";
RL   Res. Microbiol. 142:283-288(1991).
RN   [7]
RP   IDENTIFICATION OF GENE.
RX   PubMed=8195095; DOI=10.1128/jb.176.11.3383-3385.1994;
RA   Lundegaard C., Jensen K.F.;
RT   "The DNA damage-inducible dinD gene of Escherichia coli is equivalent to
RT   orfY upstream of pyrE.";
RL   J. Bacteriol. 176:3383-3385(1994).
RN   [8]
RP   IDENTIFICATION OF GENE.
RX   PubMed=8057377; DOI=10.1006/jmbi.1994.1528;
RA   Lewis K.L., Harlow G.R., Gregg-Jolly L.A., Mount D.W.;
RT   "Identification of high affinity binding sites for LexA which define new
RT   DNA damage-inducible genes in Escherichia coli.";
RL   J. Mol. Biol. 241:507-523(1994).
RN   [9]
RP   IDENTIFICATION OF GENE.
RX   PubMed=8002613; DOI=10.1128/jb.177.1.156-165.1995;
RA   Ohmori H., Saito M., Yasuda T., Nagata T., Fujii T., Wachi M., Nagai K.;
RT   "The pcsA gene is identical to dinD in Escherichia coli.";
RL   J. Bacteriol. 177:156-165(1995).
CC   -!- MISCELLANEOUS: Essential for E.coli under special growth condition.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA61998.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; X14235; CAA32452.1; -; Genomic_DNA.
DR   EMBL; L10328; AAA61998.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC76669.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77648.1; -; Genomic_DNA.
DR   EMBL; M31529; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; G65165; G65165.
DR   RefSeq; NP_418102.2; NC_000913.3.
DR   RefSeq; WP_001350563.1; NZ_LN832404.1.
DR   AlphaFoldDB; P23840; -.
DR   BioGRID; 4262564; 171.
DR   BioGRID; 852460; 2.
DR   IntAct; P23840; 8.
DR   STRING; 511145.b3645; -.
DR   PaxDb; P23840; -.
DR   PRIDE; P23840; -.
DR   EnsemblBacteria; AAC76669; AAC76669; b3645.
DR   EnsemblBacteria; BAE77648; BAE77648; BAE77648.
DR   GeneID; 948153; -.
DR   KEGG; ecj:JW3620; -.
DR   KEGG; eco:b3645; -.
DR   PATRIC; fig|511145.12.peg.3765; -.
DR   EchoBASE; EB1179; -.
DR   eggNOG; COG3645; Bacteria.
DR   HOGENOM; CLU_065349_0_0_6; -.
DR   InParanoid; P23840; -.
DR   OMA; FMLTRYA; -.
DR   BioCyc; EcoCyc:EG11193-MON; -.
DR   PRO; PR:P23840; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:EcoliWiki.
DR   GO; GO:0009432; P:SOS response; IMP:EcoCyc.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..274
FT                   /note="DNA damage-inducible protein D"
FT                   /id="PRO_0000079902"
SQ   SEQUENCE   274 AA;  31078 MW;  27ADCBAF6AF98D12 CRC64;
     MNEHHQPFEE IKLINANGAE QWSARQLGKL LGYSEYRHFI PVLTRAKEAC ENSGHTIDDH
     FEEILDMVKI GSNAKRALKD IVLSRYACYL VVQNGDPAKP VIAAGQTYFA IQTRRQELAD
     DEAFKQLRED EKRLFLRNEL KEHNKQLVEA AQQAGVATAT DFAIFQNHGY QGLYGGLDQK
     AIHQRKGLKK NQKILDHMGS TELAANLFRA TQTEEKLKRD GVNSKQQANT THFDVGRKVR
     QTIQELGGTM PEELPTPQVS IKQLENSVKI TEKK