ID   DIPA_PROTE              Reviewed;          82 AA.
AC   P10836;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Diptericin-A;
OS   Protophormia terraenovae (Northern blowfly) (Lucilia terraenovae).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC   Calliphoridae; Chrysomyinae; Protophormia.
OX   NCBI_TaxID=34676;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Hemolymph;
RX   PubMed=3276515; DOI=10.1111/j.1432-1033.1988.tb13752.x;
RA   Dimarcq J.-L., Keppi E., Dunbar B., Lambert J., Reichhart J.-M.,
RA   Hoffmann D., Rankine S.M., Fothergill J.E., Hoffmann J.A.;
RT   "Insect immunity. Purification and characterization of a family of novel
RT   inducible antibacterial proteins from immunized larvae of the dipteran
RT   Phormia terranovae and complete amino-acid sequence of the predominant
RT   member, diptericin A.";
RL   Eur. J. Biochem. 171:17-22(1988).
CC   -!- FUNCTION: Has activity against E.coli.
CC   -!- MISCELLANEOUS: There seems to be a family of diptericin in
CC       protophormia. Diptericin A is the predominant member.
CC   -!- SIMILARITY: Belongs to the attacin/sarcotoxin-2 family. {ECO:0000305}.
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DR   PIR; S00265; S00265.
DR   AlphaFoldDB; P10836; -.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Antibiotic; Antimicrobial; Direct protein sequencing; Immunity;
KW   Innate immunity.
FT   CHAIN           1..82
FT                   /note="Diptericin-A"
FT                   /id="PRO_0000127107"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          45..69
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         82
FT                   /note="Phenylalanine amide"
FT                   /evidence="ECO:0000250|UniProtKB:P18684"
SQ   SEQUENCE   82 AA;  8619 MW;  6E51E4C3C0FFE80F CRC64;
     DEKPKLILPT PAPPNLPQLV GGGGGNRKDG FGVSVDAHQK VWTSDNGGHS IGVSPGYSQH
     LPGPYGNSRP DYRIGAGYSY NF