DIR16_ARATH
ID DIR16_ARATH Reviewed; 243 AA.
AC Q7Y225; Q9LIQ5;
DT 26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Dirigent protein 16;
DE Short=AtDIR16;
DE Flags: Precursor;
GN Name=DIR16; OrderedLocusNames=At3g24020; ORFNames=F14O13.21;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17590394; DOI=10.1016/j.phytochem.2007.04.042;
RA Ralph S.G., Jancsik S., Bohlmann J.;
RT "Dirigent proteins in conifer defense II: Extended gene discovery,
RT phylogeny, and constitutive and stress-induced gene expression in spruce
RT (Picea spp.).";
RL Phytochemistry 68:1975-1991(2007).
CC -!- FUNCTION: Dirigent proteins impart stereoselectivity on the phenoxy
CC radical-coupling reaction, yielding optically active lignans from two
CC molecules of coniferyl alcohol in the biosynthesis of lignans,
CC flavonolignans, and alkaloids and thus plays a central role in plant
CC secondary metabolism. {ECO:0000250}.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the plant dirigent protein family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB03020.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP001297; BAB03020.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE76845.1; -; Genomic_DNA.
DR EMBL; BT008336; AAP37695.1; -; mRNA.
DR EMBL; AK228024; BAE99986.1; -; mRNA.
DR RefSeq; NP_189044.1; NM_113307.2.
DR AlphaFoldDB; Q7Y225; -.
DR SMR; Q7Y225; -.
DR STRING; 3702.AT3G24020.1; -.
DR PaxDb; Q7Y225; -.
DR ProteomicsDB; 222146; -.
DR EnsemblPlants; AT3G24020.1; AT3G24020.1; AT3G24020.
DR GeneID; 821987; -.
DR Gramene; AT3G24020.1; AT3G24020.1; AT3G24020.
DR KEGG; ath:AT3G24020; -.
DR Araport; AT3G24020; -.
DR TAIR; locus:2076156; AT3G24020.
DR eggNOG; ENOG502QT90; Eukaryota.
DR HOGENOM; CLU_059816_1_0_1; -.
DR InParanoid; Q7Y225; -.
DR OMA; DPVFELY; -.
DR OrthoDB; 1122999at2759; -.
DR PhylomeDB; Q7Y225; -.
DR PRO; PR:Q7Y225; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q7Y225; baseline and differential.
DR GO; GO:0048046; C:apoplast; IEA:UniProtKB-SubCell.
DR GO; GO:0009699; P:phenylpropanoid biosynthetic process; IEA:UniProt.
DR Gene3D; 2.40.480.10; -; 1.
DR InterPro; IPR044859; Allene_oxi_cyc_Dirigent.
DR InterPro; IPR004265; Dirigent.
DR PANTHER; PTHR46215; PTHR46215; 1.
DR Pfam; PF03018; Dirigent; 1.
PE 2: Evidence at transcript level;
KW Apoplast; Reference proteome; Secreted; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..243
FT /note="Dirigent protein 16"
FT /id="PRO_0000422847"
SQ SEQUENCE 243 AA; 25317 MW; 981E28B2C8F81597 CRC64;
MMIKQSPFLL LTTILFTVAV FVAALDPAPE DPIFELYMHD LLGGSSPTAR PITGLLGNIY
NGQVPFAKQI GFTPPENGIA IPNANGALPT VNGINGVPLG TGLSGTAYSG QNLNGIQTQL
GPDGLSLGFG TITVIDDILT SGPDLGSQPL GKAQGVYVAS SADGSTQMMA FTAMLEGGEY
NDNLNFYGIY RIGSAMSHLS VTGGTGRFKN ACGFAEVRPL IPSGQHEVDG AESLLRIIVH
LKY
