ID   DIR7_ARATH              Reviewed;         186 AA.
AC   Q9LID5;
DT   26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Dirigent protein 7;
DE            Short=AtDIR7;
DE   Flags: Precursor;
GN   Name=DIR7; OrderedLocusNames=At3g13650; ORFNames=MMM17.4;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11910074; DOI=10.1126/science.1071006;
RA   Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA   Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA   Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA   Shinagawa A., Shinozaki K.;
RT   "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL   Science 296:141-145(2002).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Cheuk R.F., Chen H., Kim C.J., Shinn P., Carninci P., Hayashizaki Y.,
RA   Ishida J., Kamiya A., Kawai J., Narusaka M., Sakurai T., Satou M., Seki M.,
RA   Shinozaki K., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=17590394; DOI=10.1016/j.phytochem.2007.04.042;
RA   Ralph S.G., Jancsik S., Bohlmann J.;
RT   "Dirigent proteins in conifer defense II: Extended gene discovery,
RT   phylogeny, and constitutive and stress-induced gene expression in spruce
RT   (Picea spp.).";
RL   Phytochemistry 68:1975-1991(2007).
CC   -!- FUNCTION: Dirigent proteins impart stereoselectivity on the phenoxy
CC       radical-coupling reaction, yielding optically active lignans from two
CC       molecules of coniferyl alcohol in the biosynthesis of lignans,
CC       flavonolignans, and alkaloids and thus plays a central role in plant
CC       secondary metabolism. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the plant dirigent protein family.
CC       {ECO:0000305}.
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DR   EMBL; AP001307; BAB01912.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE75387.1; -; Genomic_DNA.
DR   EMBL; AK118030; BAC42662.1; -; mRNA.
DR   EMBL; BT010587; AAQ89609.1; -; mRNA.
DR   RefSeq; NP_187974.1; NM_112211.3.
DR   AlphaFoldDB; Q9LID5; -.
DR   SMR; Q9LID5; -.
DR   STRING; 3702.AT3G13650.1; -.
DR   PaxDb; Q9LID5; -.
DR   PRIDE; Q9LID5; -.
DR   ProteomicsDB; 224165; -.
DR   EnsemblPlants; AT3G13650.1; AT3G13650.1; AT3G13650.
DR   GeneID; 820569; -.
DR   Gramene; AT3G13650.1; AT3G13650.1; AT3G13650.
DR   KEGG; ath:AT3G13650; -.
DR   Araport; AT3G13650; -.
DR   TAIR; locus:2091521; AT3G13650.
DR   eggNOG; ENOG502RXST; Eukaryota.
DR   HOGENOM; CLU_087111_2_1_1; -.
DR   InParanoid; Q9LID5; -.
DR   OMA; WFDQKSG; -.
DR   OrthoDB; 1307715at2759; -.
DR   PhylomeDB; Q9LID5; -.
DR   PRO; PR:Q9LID5; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LID5; baseline and differential.
DR   Genevisible; Q9LID5; AT.
DR   GO; GO:0048046; C:apoplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0009699; P:phenylpropanoid biosynthetic process; IEA:UniProt.
DR   Gene3D; 2.40.480.10; -; 1.
DR   InterPro; IPR044859; Allene_oxi_cyc_Dirigent.
DR   InterPro; IPR004265; Dirigent.
DR   PANTHER; PTHR21495; PTHR21495; 1.
DR   Pfam; PF03018; Dirigent; 1.
PE   2: Evidence at transcript level;
KW   Apoplast; Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..186
FT                   /note="Dirigent protein 7"
FT                   /id="PRO_0000422838"
FT   CARBOHYD        70
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        91
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        126
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   186 AA;  20429 MW;  2F56BF457D98826F CRC64;
     MAKLILIIVT QILLIAAVVS ARKGENFAKT IDKKHFGLRK EKLTHFRVYW HDILSGSNPS
     SVVINPPISN SSFFGSVTVI DNRLTTEVAV NSTLVGQAQG IYAATGQRDA SALMVMNFAF
     KTGKYNGSSI AILGRNAVLT KVREMPVIGG SGLFRFARGY VEARTMWFDQ KSGDATVEYS
     CYVLHY