ID   ADCC_STRR6              Reviewed;         234 AA.
AC   P0A2U7; O87862;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Zinc transport system ATP-binding protein AdcC;
GN   Name=adcC; OrderedLocusNames=spr1977;
OS   Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=171101;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9765793; DOI=10.1016/s0923-2508(97)87643-7;
RA   Dintilhac A., Claverys J.-P.;
RT   "The adc locus, which affects competence for genetic transformation in
RT   Streptococcus pneumoniae, encodes an ABC transporter with a putative
RT   lipoprotein homologous to a family of streptococcal adhesins.";
RL   Res. Microbiol. 148:119-131(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-255 / R6;
RX   PubMed=11544234; DOI=10.1128/jb.183.19.5709-5717.2001;
RA   Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S.,
RA   DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA   Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J.,
RA   Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S.M., McHenney M.,
RA   McLeaster K., Mundy C.W., Nicas T.I., Norris F.H., O'Gara M., Peery R.B.,
RA   Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA   Young-Bellido M., Zhao G., Zook C.A., Baltz R.H., Jaskunas S.R.,
RA   Rosteck P.R. Jr., Skatrud P.L., Glass J.I.;
RT   "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL   J. Bacteriol. 183:5709-5717(2001).
CC   -!- FUNCTION: Part of the ATP-driven transport system AdcABC for zinc.
CC       Required for transformability (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z71552; CAA96186.1; -; Genomic_DNA.
DR   EMBL; AE007317; AAL00779.1; -; Genomic_DNA.
DR   PIR; F98118; F98118.
DR   PIR; T46754; T46754.
DR   RefSeq; NP_359568.1; NC_003098.1.
DR   RefSeq; WP_001269474.1; NC_003098.1.
DR   AlphaFoldDB; P0A2U7; -.
DR   SMR; P0A2U7; -.
DR   STRING; 171101.spr1977; -.
DR   EnsemblBacteria; AAL00779; AAL00779; spr1977.
DR   GeneID; 60233434; -.
DR   KEGG; spr:spr1977; -.
DR   PATRIC; fig|171101.6.peg.2140; -.
DR   eggNOG; COG1121; Bacteria.
DR   HOGENOM; CLU_000604_1_11_9; -.
DR   OMA; GHDHVHP; -.
DR   Proteomes; UP000000586; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Competence; Ion transport; Nucleotide-binding;
KW   Reference proteome; Transport; Zinc; Zinc transport.
FT   CHAIN           1..234
FT                   /note="Zinc transport system ATP-binding protein AdcC"
FT                   /id="PRO_0000091923"
FT   DOMAIN          4..234
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         36..43
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   234 AA;  26542 MW;  2AF782EF93D5C1A0 CRC64;
     MRYITVEDLS FYYDKEPVLE HINYCVDSGE FVTLTGENGA AKTTLIKASL GILQPRIGKV
     AISKTNTQGK KLRIAYLPQQ IASFNAGFPS TVYEFVKSGR YPRKGWFRRL NAHDEEHIKA
     SLDSVGMWEH RDKRLGSLSG GQKQRAVIAR MFASDPDVFI LDEPTTGMDA GSKNEFYELM
     HHSAHHHGKA VLMITHDPEE VKDYADRNIH LVRNQDSPWR CFNVHENGQE VGHA