ID   ADCE_DICDI              Reviewed;         564 AA.
AC   Q55GN8;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Arrestin domain-containing protein E;
GN   Name=adcE; ORFNames=DDB_G0267584;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000003; EAL73245.1; -; Genomic_DNA.
DR   RefSeq; XP_647146.1; XM_642054.1.
DR   AlphaFoldDB; Q55GN8; -.
DR   STRING; 44689.DDB0267093; -.
DR   PaxDb; Q55GN8; -.
DR   EnsemblProtists; EAL73245; EAL73245; DDB_G0267584.
DR   GeneID; 8615949; -.
DR   KEGG; ddi:DDB_G0267584; -.
DR   dictyBase; DDB_G0267584; adcE.
DR   eggNOG; ENOG502SBW6; Eukaryota.
DR   HOGENOM; CLU_483515_0_0_1; -.
DR   InParanoid; Q55GN8; -.
DR   OMA; ICAGCQK; -.
DR   PRO; PR:Q55GN8; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.640; -; 1.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR011022; Arrestin_C-like.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR007330; MIT_dom.
DR   InterPro; IPR036181; MIT_dom_sf.
DR   InterPro; IPR001781; Znf_LIM.
DR   Pfam; PF00412; LIM; 1.
DR   Pfam; PF04212; MIT; 2.
DR   SMART; SM01017; Arrestin_C; 1.
DR   SMART; SM00132; LIM; 1.
DR   SMART; SM00745; MIT; 2.
DR   SUPFAM; SSF116846; SSF116846; 2.
DR   SUPFAM; SSF81296; SSF81296; 1.
DR   PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE   4: Predicted;
KW   LIM domain; Metal-binding; Reference proteome; Zinc.
FT   CHAIN           1..564
FT                   /note="Arrestin domain-containing protein E"
FT                   /id="PRO_0000363158"
FT   DOMAIN          348..413
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
FT   REGION          74..150
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          245..286
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        258..286
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   564 AA;  63571 MW;  20324A6A973AB1DD CRC64;
     MSSEILQTGL QLVKSAIDAD NQKNYSLACN LYDQAVLNLK LALVAEREPS KNALISSKIE
     EYSQRNKFIK NLLSQQPQSS QPSQPQQSQF SFPSVPSSIS PSINQQQQQQ QQQINNNNNS
     ILSSFPSAGN TNNNNNNTSN GFSPPNLNKN EQLSKLNSLS IGNNQSTNRQ LSRVEAYEAA
     KNFSLKGRKE EEVKNYRGAS QCYEEACNYY LMAIKSEPDP TLKKNLSDEA KIYLDRIEVL
     KPFAASQPQP QQPQQPQPQQ PQQQQFQQQS YNNNNSTQSM LSSFPSFNGS TNSLNNSLNN
     SNNNFNQILT NSNMPIAQQN FLQNHQFNQS NNSFNNATSS LPLTFSGDKC AACDALLSTN
     SIKALDRNWH AECFQVSIIC AGCQKPFALS NLSLKVKDNR AYHPMCFEST TGLSQEEIRT
     FVGSSKQLFF SIQLQRKFYR AGETIQFGFT IDNGTTKKVE KVVAYLLMTE TRMEITGTAY
     ERKPKRTIKK LGRCEFHHSN RFPLIKDRFE GDFFYSIPPN ILPSEVTGVD ASFVREYQLI
     VKCVGPPLKI MTVKLKFNLT ILDK