ID   ADCF_DICDI              Reviewed;        1030 AA.
AC   Q54HT7;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Arrestin domain-containing protein F;
GN   Name=adcF; ORFNames=DDB_G0289229;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the arrestin family. {ECO:0000305}.
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DR   EMBL; AAFI02000131; EAL62848.1; -; Genomic_DNA.
DR   RefSeq; XP_636352.1; XM_631260.1.
DR   AlphaFoldDB; Q54HT7; -.
DR   STRING; 44689.DDB0267094; -.
DR   PaxDb; Q54HT7; -.
DR   EnsemblProtists; EAL62848; EAL62848; DDB_G0289229.
DR   GeneID; 8627025; -.
DR   KEGG; ddi:DDB_G0289229; -.
DR   dictyBase; DDB_G0289229; adcF.
DR   eggNOG; ENOG502RDNR; Eukaryota.
DR   HOGENOM; CLU_294481_0_0_1; -.
DR   InParanoid; Q54HT7; -.
DR   OMA; ENNINCK; -.
DR   Reactome; R-DDI-844456; The NLRP3 inflammasome.
DR   PRO; PR:Q54HT7; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IBA:GO_Central.
DR   Gene3D; 2.60.40.640; -; 3.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR011022; Arrestin_C-like.
DR   InterPro; IPR014756; Ig_E-set.
DR   Pfam; PF02752; Arrestin_C; 1.
DR   SMART; SM01017; Arrestin_C; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..1030
FT                   /note="Arrestin domain-containing protein F"
FT                   /id="PRO_0000363159"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          119..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          539..572
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          885..931
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          320..374
FT                   /evidence="ECO:0000255"
FT   COILED          544..577
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        10..24
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        545..566
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        887..901
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        902..931
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1030 AA;  117724 MW;  76EBA84EDAF3E6CD CRC64;
     MEIIKENNEN DGENINNIPK KKSGSKRQLS FKKKWKASFK KNDFVNSHGI NYNKSVGVGG
     NSGMPQRRNS IVAKPIGLTS YKINHNHNYQ SQKLTWKYTS PTNSSLNLKN SDLKYLNNEN
     KNISDNSNFD DGEEDDTDNK KNINNKNNNN NNPLTDIINI EEKIANTTTT TTNTTTINTE
     TKNDIDTTIS KLNNFYDNDE TNNNIQNETD GNNNNSFSIS NNLIIKEKNN NNNKNDNGDS
     DDDEDCKIII LDKPHIENLN DKNKQILSQP HTLTQPLTPT SNNTHKSTLF KKLELPPAPP
     SPPQPPVFQN LNNCDNIIQH QLENNCDAKN KSINIYNNEF DFKNNNNNII ENNENFEKNL
     NLLNNNNNFY HNNNLKKSKD NILKKSNNNI NNINNININN NNNNNKKSKS KIKIFKKLLN
     NNIDRLNKNN MDNVLMKSQI IQINGAEIDD GNNYFNKNDQ QHIEDNLMFL NETSQTNNAT
     CEIDNLIDSI KINLSNGYFI AGQKVTGNLE ISLNQDIKTS GLNLKWKVFE HVIINHYQSP
     QSPQKLNKKD KEKEKEKEKE NDNDNENNNS ESLIRDQSFE LIDASSLKSF SNSSNCGSSL
     RNSQSINLNN YNFNNYKGGT LKKNSKIFNV LKNSSSITNF LKINPLTSSS SDFSLNSSSN
     YNLNLFNENR LIYKNQEKKT IYESGDSIFQ TDDNGGIMNS GLHIIPFSFL LPSHLPSSFS
     DFTIDKETNE KILSAIIYKL SISFQDILYE EEDNDENNNN NFYNQHDDNE DNENIRNKKE
     YLKSLYELLK DYKIKKSFTV CEPSIIAAKV NEIPIRMEKK KSFLVNSGQI SLKVALKRTI
     FFANEKIPIN IKIENASSRS IDYILISIKK IQNISLSLIK KSKNNNEKQQ QQIEKDNDEQ
     QPNITDLTLS PSSSSFLSNS SNTSSSKNNN NNNNNLIFKK CTFKTSQRFN GVDAHCNFSD
     TILFDTNEIK GFNQTTNGTL IKCHYNIVIQ CFVKRAFNVV CRIPILFGAL PENNLTSIFN
     DEYQLNLLNM