DIUX_CAMFO
ID DIUX_CAMFO Reviewed; 105 AA.
AC E2AZE8;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 14-OCT-2015, sequence version 2.
DT 25-MAY-2022, entry version 19.
DE RecName: Full=Diuretic hormone class 2 {ECO:0000312|EMBL:EFN61187.1};
DE AltName: Full=DH(31) {ECO:0000303|PubMed:25641051};
DE AltName: Full=Diuretic peptide {ECO:0000250|UniProtKB:P85826};
DE Short=DP {ECO:0000250|UniProtKB:P85826};
DE Flags: Precursor;
GN ORFNames=EAG_12746 {ECO:0000312|EMBL:EFN61187.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
RN [2] {ECO:0000305}
RP PROTEIN SEQUENCE OF 66-96, TISSUE SPECIFICITY, MASS SPECTROMETRY,
RP IDENTIFICATION BY MASS SPECTROMETRY, AND AMIDATION AT PRO-96.
RX PubMed=25641051; DOI=10.1021/pr5011636;
RA Schmitt F., Vanselow J.T., Schlosser A., Kahnt J., Roessler W., Wegener C.;
RT "Neuropeptidomics of the carpenter ant Camponotus floridanus.";
RL J. Proteome Res. 14:1504-1514(2015).
CC -!- FUNCTION: Regulation of fluid secretion. Stimulates Malpighian tubules
CC fluid secretion. {ECO:0000250|UniProtKB:P85826}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:25641051}.
CC -!- TISSUE SPECIFICITY: Expressed in central brain, antennal lobes,
CC retrocerebral complex and gnathal, thoracic and abdominal ganglia but
CC not in optical lobes (at protein level). {ECO:0000269|PubMed:25641051}.
CC -!- MASS SPECTROMETRY: Mass=2986.53; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:25641051};
CC -!- SIMILARITY: Belongs to the diuretic hormone class 2 family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EFN61187.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305|PubMed:25641051};
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DR EMBL; GL444207; EFN61187.1; ALT_SEQ; Genomic_DNA.
DR AlphaFoldDB; E2AZE8; -.
DR STRING; 104421.E2AZE8; -.
DR InParanoid; E2AZE8; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008613; F:diuretic hormone activity; IEA:InterPro.
DR GO; GO:0007589; P:body fluid secretion; IEA:InterPro.
DR InterPro; IPR034439; DH2-like.
DR PANTHER; PTHR41146; PTHR41146; 1.
PE 1: Evidence at protein level;
KW Amidation; Cleavage on pair of basic residues; Direct protein sequencing;
KW Hormone; Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT PROPEP 24..63
FT /evidence="ECO:0000305|PubMed:25641051"
FT /id="PRO_0000434209"
FT PEPTIDE 66..96
FT /note="Diuretic hormone class 2"
FT /evidence="ECO:0000269|PubMed:25641051"
FT /id="PRO_0000434210"
FT PROPEP 101..105
FT /evidence="ECO:0000305|PubMed:25641051"
FT /id="PRO_0000434211"
FT MOD_RES 96
FT /note="Proline amide"
FT /evidence="ECO:0000269|PubMed:25641051"
SQ SEQUENCE 105 AA; 11640 MW; D9F44E6650B5C1B2 CRC64;
MTVLCTLMAF VMVVAISSLT VDAIPHSHES YWDQQDDIDR DEFLELLSRL SRTVMNRPEM
ENSKRGLDLG LSRGFSGSQA AKHLMGLAAA NYAGGPGRRR RSEQA
