ID   DIVIB_LACRG             Reviewed;         284 AA.
AC   C7TC36; C8UTQ4;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Cell division protein DivIB {ECO:0000255|HAMAP-Rule:MF_00912};
GN   Name=divIB {ECO:0000255|HAMAP-Rule:MF_00912}; Synonyms=ftsQ;
GN   OrderedLocusNames=LRHM_1231, LGG_01284;
OS   Lacticaseibacillus rhamnosus (strain ATCC 53103 / LMG 18243 / GG)
OS   (Lactobacillus rhamnosus).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lacticaseibacillus.
OX   NCBI_TaxID=568703;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53103 / LMG 18243 / GG;
RX   PubMed=19820099; DOI=10.1128/jb.01287-09;
RA   Morita H., Toh H., Oshima K., Murakami M., Taylor T.D., Igimi S.,
RA   Hattori M.;
RT   "Complete genome sequence of the probiotic Lactobacillus rhamnosus ATCC
RT   53103.";
RL   J. Bacteriol. 191:7630-7631(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53103 / LMG 18243 / GG;
RX   PubMed=19805152; DOI=10.1073/pnas.0908876106;
RA   Kankainen M., Paulin L., Tynkkynen S., von Ossowski I., Reunanen J.,
RA   Partanen P., Satokari R., Vesterlund S., Hendrickx A.P., Lebeer S.,
RA   De Keersmaecker S.C., Vanderleyden J., Hamalainen T., Laukkanen S.,
RA   Salovuori N., Ritari J., Alatalo E., Korpela R., Mattila-Sandholm T.,
RA   Lassig A., Hatakka K., Kinnunen K.T., Karjalainen H., Saxelin M.,
RA   Laakso K., Surakka A., Palva A., Salusjarvi T., Auvinen P., de Vos W.M.;
RT   "Comparative genomic analysis of Lactobacillus rhamnosus GG reveals pili
RT   containing a human- mucus binding protein.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:17193-17198(2009).
CC   -!- FUNCTION: Cell division protein that may be involved in stabilizing or
CC       promoting the assembly of the division complex. {ECO:0000255|HAMAP-
CC       Rule:MF_00912}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00912};
CC       Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_00912}.
CC       Note=Localizes to the division septum. {ECO:0000255|HAMAP-
CC       Rule:MF_00912}.
CC   -!- SIMILARITY: Belongs to the FtsQ/DivIB family. DivIB subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00912}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAI41758.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AP011548; BAI41758.1; ALT_INIT; Genomic_DNA.
DR   EMBL; FM179322; CAR87179.1; -; Genomic_DNA.
DR   AlphaFoldDB; C7TC36; -.
DR   KEGG; lrg:LRHM_1231; -.
DR   KEGG; lrh:LGG_01284; -.
DR   PATRIC; fig|568703.30.peg.1278; -.
DR   HOGENOM; CLU_046278_0_0_9; -.
DR   OMA; YMNDGNE; -.
DR   Proteomes; UP000002067; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00912; DivIB; 1.
DR   InterPro; IPR026580; DivIB.
DR   InterPro; IPR034746; POTRA.
DR   InterPro; IPR013685; POTRA_FtsQ_type.
DR   Pfam; PF08478; POTRA_1; 1.
DR   PROSITE; PS51779; POTRA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..284
FT                   /note="Cell division protein DivIB"
FT                   /id="PRO_0000414774"
FT   TOPO_DOM        1..56
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   TOPO_DOM        78..284
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   DOMAIN          79..150
FT                   /note="POTRA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   284 AA;  32031 MW;  A26EAC1850CCC8A0 CRC64;
     MAWLRKKEQQ SDPLTPWQQY QARQQQTPRH DRRQKPKLDV NLPKIQTLRR RKLVKNLVLI
     LLPLLLLLGV FGYFASPLSK VGLVSVQGVT TVPDQQVINA TKLSDDDLML SVAFHKNAIA
     QRVQKSLPEI KTASLTIKGF NRIIIKTSEY QTVGYVYQKH AYHKILVTGE VLAAGTQTPV
     TTYPVFSGFT AKELPQMITL LKQFPAAIRR DISEIDASRG DANPNQIALN MNDGYRIIAD
     TRTIAKKIKY YPAIVSQVKQ KGVVDLEVGA FWRPYSSSEK SSND