ID   DIVIB_STAAR             Reviewed;         440 AA.
AC   Q6GHQ1;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Cell division protein DivIB {ECO:0000255|HAMAP-Rule:MF_00912};
GN   Name=divIB {ECO:0000255|HAMAP-Rule:MF_00912}; OrderedLocusNames=SAR1160;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- FUNCTION: Cell division protein that may be involved in stabilizing or
CC       promoting the assembly of the division complex. {ECO:0000255|HAMAP-
CC       Rule:MF_00912}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00912};
CC       Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_00912}.
CC       Note=Localizes to the division septum. {ECO:0000255|HAMAP-
CC       Rule:MF_00912}.
CC   -!- SIMILARITY: Belongs to the FtsQ/DivIB family. DivIB subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00912}.
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DR   EMBL; BX571856; CAG40162.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6GHQ1; -.
DR   SMR; Q6GHQ1; -.
DR   PRIDE; Q6GHQ1; -.
DR   KEGG; sar:SAR1160; -.
DR   HOGENOM; CLU_046278_3_1_9; -.
DR   OMA; YMNDGNE; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00912; DivIB; 1.
DR   InterPro; IPR026580; DivIB.
DR   InterPro; IPR034746; POTRA.
DR   InterPro; IPR013685; POTRA_FtsQ_type.
DR   Pfam; PF08478; POTRA_1; 1.
DR   PROSITE; PS51779; POTRA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..440
FT                   /note="Cell division protein DivIB"
FT                   /id="PRO_0000414785"
FT   TOPO_DOM        1..174
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   TOPO_DOM        196..440
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   DOMAIN          196..264
FT                   /note="POTRA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   REGION          1..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          123..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          397..440
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..27
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..76
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        77..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        136..154
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        421..440
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   440 AA;  50269 MW;  212B623098C87BD6 CRC64;
     MMDDKTKNDQ QESNEDKDEL ELFTRNTSKK RRQRKRSKAT HFSNQNKDDT SQQADFDEEI
     YLINKDFKKE QGNEENNDSA SSHANDNNID DSTDSNIENE DYRYNQETDD QNESNGIAVD
     NEQHQSAPNE QNSDSNDEET VTKKERKSKV TQLKPLTLEE KRKVRRKRQK RIQYSVITIL
     VLLIAVILIY MFSPLSKIAH VNINGNNHVS TSKINKVLGV KNDSRMYTFS KKNAINDLEE
     DPLIKSVEIH KQLPNTLNVD ITENEIIALV KYKGKYLPLL ENGKLLKGSN DVKINDAPVM
     DGFKGTKEDD MIKALSEMTP EVRRYIAEVT YAPSKNKQSR IELFTTDGLQ VIGDISTISK
     KMKYYPQMSQ SLARDSSGKL KTRGYIDLSV GASFIPYRGN TSTQSESDKN VTKSSQEENQ
     AKEELQSVLN KINKQSSKNN