ID   DIVIB_STRPD             Reviewed;         382 AA.
AC   Q1JG12;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   13-JUN-2006, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Cell division protein DivIB {ECO:0000255|HAMAP-Rule:MF_00912};
GN   Name=divIB {ECO:0000255|HAMAP-Rule:MF_00912};
GN   OrderedLocusNames=MGAS10270_Spy1267;
OS   Streptococcus pyogenes serotype M2 (strain MGAS10270).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=370552;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGAS10270;
RX   PubMed=16636287; DOI=10.1073/pnas.0510279103;
RA   Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R.,
RA   Musser J.M.;
RT   "Molecular genetic anatomy of inter- and intraserotype variation in the
RT   human bacterial pathogen group A Streptococcus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006).
CC   -!- FUNCTION: Cell division protein that may be involved in stabilizing or
CC       promoting the assembly of the division complex. {ECO:0000255|HAMAP-
CC       Rule:MF_00912}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00912};
CC       Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_00912}.
CC       Note=Localizes to the division septum. {ECO:0000255|HAMAP-
CC       Rule:MF_00912}.
CC   -!- SIMILARITY: Belongs to the FtsQ/DivIB family. DivIB subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00912}.
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DR   EMBL; CP000260; ABF34332.1; -; Genomic_DNA.
DR   RefSeq; WP_020905323.1; NC_008022.1.
DR   AlphaFoldDB; Q1JG12; -.
DR   EnsemblBacteria; ABF34332; ABF34332; MGAS10270_Spy1267.
DR   KEGG; sph:MGAS10270_Spy1267; -.
DR   HOGENOM; CLU_046278_1_0_9; -.
DR   OMA; YMNDGNE; -.
DR   Proteomes; UP000002436; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00912; DivIB; 1.
DR   InterPro; IPR026580; DivIB.
DR   InterPro; IPR034746; POTRA.
DR   InterPro; IPR013685; POTRA_FtsQ_type.
DR   Pfam; PF08478; POTRA_1; 1.
DR   PROSITE; PS51779; POTRA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..382
FT                   /note="Cell division protein DivIB"
FT                   /id="PRO_0000414791"
FT   TOPO_DOM        1..103
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   TOPO_DOM        125..382
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   DOMAIN          125..196
FT                   /note="POTRA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   REGION          36..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          322..382
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        60..83
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        338..355
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        356..375
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   382 AA;  43477 MW;  A82D97026CCE1B3A CRC64;
     MAKDKEKQSD DKLVLTEWQK RNIEFLKKKK QQAEEEKKLK EKLLSDKKAQ QQAQNASEAV
     ELKTDEKTDS QEIESETTSK PKKTKKVRQP KEKSATQIAF QKSLPVLLGA LLLMAVSIFM
     ITPYSKKKEF SVRGNHQTNL DELIKASKVK ASDYWLTLLI SPGQYERPIL RTIPWVKSVH
     LSYHFPNHFL FNVIEFEIIA YAQVENGFQP ILENGKRVDK VRASELPKSF LILNLKDEKA
     IQQLVKQLTT LPKKLVKNIK SVSLANSKTT ADLLLIEMHD GNVVRVPQSQ LTLKLPYYQK
     LKKNLENDSI VDMEVGIYTT TQEIENQPEV PLTPEQNAAD KEGDKPGEHQ EQTDNDSETP
     ANQSSPQQTP PSPETVLEQA HG