ID   DIVIB_STRR6             Reviewed;         396 AA.
AC   Q8DQM0;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Cell division protein DivIB {ECO:0000255|HAMAP-Rule:MF_00912};
GN   Name=divIB {ECO:0000255|HAMAP-Rule:MF_00912}; OrderedLocusNames=spr0605;
OS   Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=171101;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-255 / R6;
RX   PubMed=11544234; DOI=10.1128/jb.183.19.5709-5717.2001;
RA   Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S.,
RA   DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA   Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J.,
RA   Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S.M., McHenney M.,
RA   McLeaster K., Mundy C.W., Nicas T.I., Norris F.H., O'Gara M., Peery R.B.,
RA   Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA   Young-Bellido M., Zhao G., Zook C.A., Baltz R.H., Jaskunas S.R.,
RA   Rosteck P.R. Jr., Skatrud P.L., Glass J.I.;
RT   "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL   J. Bacteriol. 183:5709-5717(2001).
CC   -!- FUNCTION: Cell division protein that may be involved in stabilizing or
CC       promoting the assembly of the division complex. {ECO:0000255|HAMAP-
CC       Rule:MF_00912}.
CC   -!- INTERACTION:
CC       Q8DQM0; P0AD68: ftsI; Xeno; NbExp=3; IntAct=EBI-6446264, EBI-548564;
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00912};
CC       Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_00912}.
CC       Note=Localizes to the division septum. {ECO:0000255|HAMAP-
CC       Rule:MF_00912}.
CC   -!- SIMILARITY: Belongs to the FtsQ/DivIB family. DivIB subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00912}.
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DR   EMBL; AE007317; AAK99409.1; -; Genomic_DNA.
DR   PIR; E97947; E97947.
DR   RefSeq; NP_358199.1; NC_003098.1.
DR   RefSeq; WP_000031166.1; NC_003098.1.
DR   AlphaFoldDB; Q8DQM0; -.
DR   IntAct; Q8DQM0; 2.
DR   STRING; 171101.spr0605; -.
DR   EnsemblBacteria; AAK99409; AAK99409; spr0605.
DR   GeneID; 60232997; -.
DR   KEGG; spr:spr0605; -.
DR   PATRIC; fig|171101.6.peg.672; -.
DR   eggNOG; COG1589; Bacteria.
DR   HOGENOM; CLU_046278_1_1_9; -.
DR   OMA; YMNDGNE; -.
DR   Proteomes; UP000000586; Chromosome.
DR   GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00912; DivIB; 1.
DR   InterPro; IPR026580; DivIB.
DR   InterPro; IPR034746; POTRA.
DR   InterPro; IPR013685; POTRA_FtsQ_type.
DR   Pfam; PF08478; POTRA_1; 1.
DR   PROSITE; PS51779; POTRA; 1.
PE   1: Evidence at protein level;
KW   Cell cycle; Cell division; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..396
FT                   /note="Cell division protein DivIB"
FT                   /id="PRO_0000414790"
FT   TOPO_DOM        1..130
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   TOPO_DOM        152..396
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00912"
FT   DOMAIN          153..223
FT                   /note="POTRA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          37..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          361..396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..65
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..116
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        361..390
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   396 AA;  45400 MW;  9ECC9031DE0D4808 CRC64;
     MSKDKKNEDK ETLEELKELS EWQKRNQEYL KKKAEEEVAL AEEKEKERQA RMGEESEKSE
     DKQDQESETD QEDSESAKEE SEEKVASSEA DKEKEEPESK EKEEQDKKLA KKATKEKPAK
     AKIPGIHILR AFTILFPSLL LLIVSAYLLS PYATMKDIRV EGTVQTTADD IRQASGIQDS
     DYTINLLLDK AKYEKQIKSN YWVESAQLVY QFPTKFTIKV KEYDIVAYYI SGENHYPILS
     SGQLETSSVS LNSLPETYLS VLFNDSEQIK VFVSELAQIS PELKAAIQKV ELAPSKVTSD
     LIRLTMNDSD EVLVPLSEMS KKLPYYSKIK PQLSEPSVVD MEAGIYSYTV ADKLIMEAEE
     KAKQEAKEAE KKQEEEQKKQ EEESNRNQTN QRSSRR