ID   DIVK_BRUA2              Reviewed;         123 AA.
AC   Q2YKN1;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Polar-differentiation response regulator DivK;
GN   Name=divK; OrderedLocusNames=BAB2_0628;
OS   Brucella abortus (strain 2308).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=359391;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2308;
RX   PubMed=16299333; DOI=10.1128/iai.73.12.8353-8361.2005;
RA   Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A.,
RA   Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.;
RT   "Whole-genome analyses of speciation events in pathogenic Brucellae.";
RL   Infect. Immun. 73:8353-8361(2005).
CC   -!- FUNCTION: Essential protein that is involved in the control of cell
CC       division, probably through the regulation of ctrA. Its phosphorylation
CC       status is regulated by PdhS (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with DivL, PleC, DivJ and PdhS. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localized at one
CC       pole of the cell. Colocalizes with PdhS (By similarity). {ECO:0000250}.
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DR   EMBL; AM040265; CAJ12794.1; -; Genomic_DNA.
DR   RefSeq; WP_002966022.1; NZ_KN046823.1.
DR   AlphaFoldDB; Q2YKN1; -.
DR   SMR; Q2YKN1; -.
DR   IntAct; Q2YKN1; 1.
DR   STRING; 359391.BAB2_0628; -.
DR   EnsemblBacteria; CAJ12794; CAJ12794; BAB2_0628.
DR   GeneID; 45125960; -.
DR   GeneID; 55592281; -.
DR   KEGG; bmf:BAB2_0628; -.
DR   PATRIC; fig|359391.11.peg.2810; -.
DR   HOGENOM; CLU_000445_69_17_5; -.
DR   OMA; RDYITKP; -.
DR   PRO; PR:Q2YKN1; -.
DR   Proteomes; UP000002719; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..123
FT                   /note="Polar-differentiation response regulator DivK"
FT                   /id="PRO_0000363205"
FT   DOMAIN          4..120
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   MOD_RES         53
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   123 AA;  13973 MW;  0D74511EB774FA24 CRC64;
     MTKSVMIVED NELNMKLFRD LIEASGYETI RTRSGLEALD LAREHHPDLI LMDIQLPEVS
     GLEVTKWLKD DEELRHIPVI AVTAFAMKGD EERIRQGGCE AYISKPISVP RFIETIKSYL
     GDA