ID   DIV_ANTMA               Reviewed;         307 AA.
AC   Q8S9H7;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Transcription factor DIVARICATA;
GN   Name=DIVARICATA;
OS   Antirrhinum majus (Garden snapdragon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Plantaginaceae; Antirrhineae; Antirrhinum.
OX   NCBI_TaxID=4151;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, DISRUPTION PHENOTYPE, AND
RP   DEVELOPMENTAL STAGE.
RX   PubMed=11937495; DOI=10.1101/gad.221002;
RA   Galego L., Almeida J.;
RT   "Role of DIVARICATA in the control of dorsoventral asymmetry in Antirrhinum
RT   flowers.";
RL   Genes Dev. 16:880-891(2002).
RN   [2]
RP   FUNCTION.
RX   PubMed=9118809; DOI=10.1242/dev.124.7.1387;
RA   Almeida J., Rocheta M., Galego L.;
RT   "Genetic control of flower shape in Antirrhinum majus.";
RL   Development 124:1387-1392(1997).
CC   -!- FUNCTION: Involved in the dorsovental asymmetry of flowers. Promotes
CC       ventral identity. {ECO:0000269|PubMed:11937495,
CC       ECO:0000269|PubMed:9118809}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00624,
CC       ECO:0000255|PROSITE-ProRule:PRU00625}.
CC   -!- DEVELOPMENTAL STAGE: Detected in the apical inflorescence meristem, in
CC       bract primordia arising in its periphery and in floral meristems
CC       produced in the axils of bracts (stages 0-3). From stage 3 to stage 8,
CC       detected in all floral organs irrespective of their dorsoventral
CC       positions. From stage 9, barely detectable in bracts, sepals, and
CC       stamens. In the corolla, however, expression was maintained and
CC       enhanced in some regions. Within ventral and lateral petals at stage 9,
CC       asymmetric pattern of expression with high levels of transcripts in the
CC       inner epidermis of the furrow and very reduced levels in the remaining
CC       cell layers. In the dorsal petals, from stage 9 onward, detected but
CC       with a more even distribution across cell layers than in the ventral
CC       petal. {ECO:0000269|PubMed:11937495}.
CC   -!- DISRUPTION PHENOTYPE: The petals are fused at the base, forming a tube
CC       that ends in the lobes. {ECO:0000269|PubMed:11937495}.
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DR   EMBL; AY077453; AAL78741.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8S9H7; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0048262; P:determination of dorsal/ventral asymmetry; IMP:UniProtKB.
DR   GO; GO:0009908; P:flower development; IMP:UniProtKB.
DR   CDD; cd00167; SANT; 2.
DR   InterPro; IPR043363; DIVARICATA-like.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017930; Myb_dom.
DR   InterPro; IPR006447; Myb_dom_plants.
DR   InterPro; IPR001005; SANT/Myb.
DR   InterPro; IPR017884; SANT_dom.
DR   PANTHER; PTHR44042; PTHR44042; 1.
DR   Pfam; PF00249; Myb_DNA-binding; 1.
DR   SMART; SM00717; SANT; 2.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
DR   PROSITE; PS51294; HTH_MYB; 1.
DR   PROSITE; PS51293; SANT; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Nucleus; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..307
FT                   /note="Transcription factor DIVARICATA"
FT                   /id="PRO_0000419440"
FT   DOMAIN          21..74
FT                   /note="SANT"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00624"
FT   DOMAIN          126..182
FT                   /note="HTH myb-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   DNA_BIND        154..178
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   REGION          109..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          196..231
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   307 AA;  34429 MW;  1A520F6B52CF34FF CRC64;
     MEILAPSSYF SSSSWFLEES RSTTRWTAAE NKAFENALAV FDENTPNRWE RVAERVPGKT
     VGDVMRQYKE LEDDVSSIEA GFVPVPGYST SSPFTLEWGS GHGFDGFKQS YGTGGRKSSS
     GRPSEQERKK GVPWTEEEHK LFLMGLKKYG KGDWRNISRN FVITRTPTQV ASHAQKYFIR
     QLSGGKDKRR ASIHDITTVN LSDNQTPSPD NKKPPSSPDH SMAQQQTSST SIHKLPFQWD
     QTSNETIMGF ASSGHHGNMF QSNPFGMNSY GFKMQGQQMQ RGGFCDTYLG SQNMAFQMQS
     GLHFPNA