ID   DJC15_XENTR             Reviewed;         149 AA.
AC   Q6DDA1;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=DnaJ homolog subfamily C member 15 {ECO:0000250|UniProtKB:Q9Y5T4};
GN   Name=dnajc15 {ECO:0000312|EMBL:AAH77694.1};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1] {ECO:0000312|EMBL:AAH77694.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo {ECO:0000312|EMBL:AAH77694.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000305}
RP   FUNCTION, AND TISSUE SPECIFICITY.
RX   PubMed=18472403; DOI=10.1016/j.mod.2008.03.001;
RA   Kyuno J., Masse K., Jones E.A.;
RT   "A functional screen for genes involved in Xenopus pronephros
RT   development.";
RL   Mech. Dev. 125:571-586(2008).
CC   -!- FUNCTION: Negative regulator of the mitochondrial respiratory chain (By
CC       similarity). Plays a role in the translocation of proteins across the
CC       mitochondrial inner membrane (By similarity). Involved in pronephric
CC       kidney development at the early tadpole stage. {ECO:0000250,
CC       ECO:0000269|PubMed:18472403}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Single-pass membrane protein {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed in the developing pronephros.
CC       {ECO:0000269|PubMed:18472403}.
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DR   EMBL; BC077694; AAH77694.1; -; mRNA.
DR   RefSeq; NP_001005145.1; NM_001005145.2.
DR   AlphaFoldDB; Q6DDA1; -.
DR   SMR; Q6DDA1; -.
DR   STRING; 8364.ENSXETP00000031900; -.
DR   PaxDb; Q6DDA1; -.
DR   DNASU; 448735; -.
DR   GeneID; 448735; -.
DR   KEGG; xtr:448735; -.
DR   CTD; 29103; -.
DR   Xenbase; XB-GENE-5716026; dnajc15.
DR   eggNOG; KOG0723; Eukaryota.
DR   HOGENOM; CLU_017633_13_3_1; -.
DR   InParanoid; Q6DDA1; -.
DR   OMA; MAMKINE; -.
DR   OrthoDB; 1600166at2759; -.
DR   TreeFam; TF320584; -.
DR   Proteomes; UP000008143; Chromosome 2.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0001405; C:PAM complex, Tim23 associated import motor; IBA:GO_Central.
DR   GO; GO:0001671; F:ATPase activator activity; IBA:GO_Central.
DR   GO; GO:0048793; P:pronephros development; IMP:UniProtKB.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR   CDD; cd06257; DnaJ; 1.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR036869; J_dom_sf.
DR   Pfam; PF00226; DnaJ; 1.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; SSF46565; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..149
FT                   /note="DnaJ homolog subfamily C member 15"
FT                   /id="PRO_0000391688"
FT   TOPO_DOM        1..34
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        58..149
FT                   /note="Mitochondrial matrix"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          95..149
FT                   /note="J"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
SQ   SEQUENCE   149 AA;  15941 MW;  D89D77FEE78288D5 CRC64;
     MATSSTGMGT SEALRYSEYM PGPNAGSSTD IDRRLGGTLI AVGLGVAAAA FAGRFAFQLW
     KPLGQVIAES AKKIPTPSLS YYYKGGFEQK MNRREASLIL GVSPSASKSK IRAAHRKIMI
     LNHPDKGGSP YMAMKINEAK DLLESTTKP