ID   DJC16_CHICK             Reviewed;         777 AA.
AC   Q5ZKZ4;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=DnaJ homolog subfamily C member 16;
DE   Flags: Precursor;
GN   Name=DNAJC16; ORFNames=RCJMB04_8j20;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type IV
CC       membrane protein {ECO:0000305}.
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DR   EMBL; AJ719940; CAG31599.1; -; mRNA.
DR   RefSeq; NP_001034419.1; NM_001039330.1.
DR   AlphaFoldDB; Q5ZKZ4; -.
DR   SMR; Q5ZKZ4; -.
DR   STRING; 9031.ENSGALP00000022198; -.
DR   PaxDb; Q5ZKZ4; -.
DR   GeneID; 429208; -.
DR   KEGG; gga:429208; -.
DR   CTD; 23341; -.
DR   VEuPathDB; HostDB:geneid_429208; -.
DR   eggNOG; KOG0715; Eukaryota.
DR   InParanoid; Q5ZKZ4; -.
DR   OrthoDB; 1253259at2759; -.
DR   PhylomeDB; Q5ZKZ4; -.
DR   PRO; PR:Q5ZKZ4; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd06257; DnaJ; 1.
DR   CDD; cd02963; TRX_DnaJ; 1.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR018253; DnaJ_domain_CS.
DR   InterPro; IPR043361; DNAJC16_TRX.
DR   InterPro; IPR036869; J_dom_sf.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   Pfam; PF00226; DnaJ; 1.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; SSF46565; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS00636; DNAJ_1; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..777
FT                   /note="DnaJ homolog subfamily C member 16"
FT                   /id="PRO_0000236687"
FT   TOPO_DOM        24..531
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        532..552
FT                   /note="Helical; Anchor for type IV membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        553..777
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          28..92
FT                   /note="J"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
FT   DOMAIN          117..243
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT   REGION          558..589
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        562..584
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        627
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   777 AA;  89415 MW;  0E188E795EC96FC6 CRC64;
     MELGRAGPAG LLLLLLLLLA AQAAPERDPY RVLGVGRSSS QADIKKAYKR LARQWHPDKN
     KDPGAEDKFI QISKAYEILS NEEKRANFDR YGDAGESQGY SQHQQRQFHH FHEGFYFDES
     FFHFPFNSER RDTSDEKYLL HFSHYINEIV PDSFKKPYLI KITSDWCFSC IHIEPVWKEV
     AQELEALGVG IGVVHAGYER RLAHHLGAHS TPSILGLING KITFFHSAVV RENLRQFVEN
     LLPGNLVEKI TDKNYIRFLS NWKKENKPHV LLFDHMPVVP LLYKLTAFAY RDYLSFGYVY
     VGLRGTEELS SQYNINVYTP TLMIFKEHID KPADVAQARD MKKQLIDDFL SQNKFLMAAR
     LTNQRLFQEL CPVKKSHRQR KHCVVLLTGE GDKFADAYEA FLTFAVANTK DTLRFAHIYN
     DRQPEFADAL LMDEEKYRGK SAVVILERRN NAGKIAYKTL EEAWQGSNED NFILLDLLDQ
     LRTDPGLLSS ETVLADLNDE LAPMFLIRWF YSTLDYILDC WDSLFHSNWR EMMPLLSLLF
     SALFILFGTV IVQAFSDSSD TRDSPASEKK DTTAKTEKND TSFNKESNSR VPKKGFVEVT
     ELTDINYNSN LVRLRPGHMN VVLILSNSTK TALLQKFALE VYTFTGSSSL HFSFLSLDKH
     REWLEYLLEF AQDAAPIPNQ YDKHFLERDY TGYVLALNGH KKYFCLFKPH RSGDEGGTLG
     ACEDYDSSLH TEARGKSSCS PGSRSLKNKL HKLSFWMERL LEGSLQRFYI PSWPALD