ID   DJC16_PONAB             Reviewed;         782 AA.
AC   Q5RCM7;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=DnaJ homolog subfamily C member 16;
DE   Flags: Precursor;
GN   Name=DNAJC16;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type IV
CC       membrane protein {ECO:0000305}.
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DR   EMBL; CR858243; CAH90480.1; -; mRNA.
DR   RefSeq; NP_001125250.1; NM_001131778.1.
DR   AlphaFoldDB; Q5RCM7; -.
DR   SMR; Q5RCM7; -.
DR   STRING; 9601.ENSPPYP00000002137; -.
DR   GeneID; 100172145; -.
DR   KEGG; pon:100172145; -.
DR   CTD; 23341; -.
DR   eggNOG; KOG0715; Eukaryota.
DR   InParanoid; Q5RCM7; -.
DR   OrthoDB; 1253259at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd06257; DnaJ; 1.
DR   CDD; cd02963; TRX_DnaJ; 1.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR018253; DnaJ_domain_CS.
DR   InterPro; IPR043361; DNAJC16_TRX.
DR   InterPro; IPR036869; J_dom_sf.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   Pfam; PF00226; DnaJ; 1.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; SSF46565; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS00636; DNAJ_1; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..782
FT                   /note="DnaJ homolog subfamily C member 16"
FT                   /id="PRO_0000236685"
FT   TOPO_DOM        26..535
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        536..556
FT                   /note="Helical; Anchor for type IV membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        557..782
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          29..93
FT                   /note="J"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
FT   DOMAIN          119..247
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT   REGION          562..593
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        565..585
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        631
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   782 AA;  90332 MW;  EDC48FC96D9D96BE CRC64;
     MEVRKLSISW QFLIVLVLIL QILSALDFDP YKVLGVSRTA SQADIKKAYK KLAREWHPDK
     NKDPGAEDKF IQISKAYEIL SNEEKRSNYD QYGDAGENQG YQKQQQQREY RFRHFHENFY
     FDESFFHFPF NSERRDSIDE KYLLHFSHYV NEVVPDSFKK PYLIKITSDW CFSCIHIEPV
     WKEVVQELEE LGVGIGVVHA GYERRLAHHL GAHSTPSILG IINGKISFFR NAVVRENLRQ
     FVESLLPGNL VEKVTGKNYV RFLSGWQQEN KPHVLLFDQT PIVPLLYKLT AFAYKDYLSF
     GYVYVGLRGT EEMTRRYNIN IYAPTLLVFK EHINKPADVI QARGMKKQII DDFITQNKHL
     LAARLTSQKL FHELCPVRRS HRQRKYCVVL LTAETTKLSK PFEAFLSFAL ANTQDTVRFV
     HVYSNRQQEF AGTLLPDGEA FQGKSAVSIL ERRNTAGRVV YKTLEDPWTG SESDKFILLG
     YLDQLRKDPA LLSSEAVLPD LTDELAPVFL LRWFYSACDY ISDCWDSIFH NNWREMMPLL
     SLIFSALFIL FGTVIVQAFS DSSDERESSP PDKEEAQEKT GKTEPSFTKE NSSKIPKKGF
     VEVTELTDVT YTSNLVRLRP GHMNVVLILS NSTKTSLLQK FALEVYTFTG SSCLHFSFLS
     LDKHREWLEY LLEFAQDAAP IPNQYDKHFM ERDYTGYVLA LNGHKKYFCL FKPQKTVEEE
     EAIGSCSDVD SSLYLGESRG KPSCGLGSRP IKGKLSKLSL WMERLLEGSL QRFYIPSWPE
     LD