ID   DJC17_BOVIN             Reviewed;         304 AA.
AC   Q2KI83;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=DnaJ homolog subfamily C member 17;
GN   Name=DNAJC17;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hypothalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May negatively affect PAX8-induced thyroglobulin/TG
CC       transcription. {ECO:0000250|UniProtKB:Q91WT4}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:D3ZSC8}. Nucleus
CC       {ECO:0000250|UniProtKB:D3ZSC8}. Note=Predominantly nuclear.
CC       {ECO:0000250|UniProtKB:D3ZSC8}.
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DR   EMBL; BC112733; AAI12734.1; -; mRNA.
DR   RefSeq; NP_001039741.1; NM_001046276.2.
DR   AlphaFoldDB; Q2KI83; -.
DR   SMR; Q2KI83; -.
DR   STRING; 9913.ENSBTAP00000017926; -.
DR   PaxDb; Q2KI83; -.
DR   PRIDE; Q2KI83; -.
DR   Ensembl; ENSBTAT00000017926; ENSBTAP00000017926; ENSBTAG00000013480.
DR   GeneID; 524795; -.
DR   KEGG; bta:524795; -.
DR   CTD; 55192; -.
DR   VEuPathDB; HostDB:ENSBTAG00000013480; -.
DR   VGNC; VGNC:53574; DNAJC17.
DR   eggNOG; KOG0691; Eukaryota.
DR   GeneTree; ENSGT00940000155132; -.
DR   HOGENOM; CLU_045732_1_0_1; -.
DR   InParanoid; Q2KI83; -.
DR   OMA; KPLHFEW; -.
DR   OrthoDB; 1405648at2759; -.
DR   TreeFam; TF321770; -.
DR   Proteomes; UP000009136; Chromosome 10.
DR   Bgee; ENSBTAG00000013480; Expressed in oocyte and 107 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0000390; P:spliceosomal complex disassembly; IBA:GO_Central.
DR   GO; GO:1901998; P:toxin transport; IEA:Ensembl.
DR   CDD; cd06257; DnaJ; 1.
DR   CDD; cd12429; RRM_DNAJC17; 1.
DR   Gene3D; 1.10.287.110; -; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR034254; DNAJC17_RRM.
DR   InterPro; IPR036869; J_dom_sf.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00226; DnaJ; 1.
DR   Pfam; PF00076; RRM_1; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; SSF46565; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome;
KW   RNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..304
FT                   /note="DnaJ homolog subfamily C member 17"
FT                   /id="PRO_0000247117"
FT   DOMAIN          11..76
FT                   /note="J"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
FT   DOMAIN          178..249
FT                   /note="RRM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          105..124
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          156..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         112
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NVM6"
SQ   SEQUENCE   304 AA;  34572 MW;  883BA9173B418790 CRC64;
     MAVTKELLQM DLYALLGIEE KAEDKEVKKA YRQKALSCHP DKNPDNPRAA ELFHQLSQAL
     EVLTDAAARA AYDKVRKAKK QAAERTQKLD ERRKKVKLDL EARERQAQAL GSEEEEESGS
     ARTLEQEIER LREEGSRQLE EQQRLIREQI RQEQEQRLTG MAKNPENKET PKLKLKWKSK
     KEAESQGGYS RDVLLQLFQK YGEVLNLVLS SKKAGTAVVE FATVKAAELA VQNEVGLVDN
     PLKISWLEGR PQSAMGHNHP GLSRGSVVSE RDYESLVMMR MRQAAERQQL IAQMQQEDQA
     GQPT