ID   DJC22_PONAB             Reviewed;         341 AA.
AC   Q5RBD7;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=DnaJ homolog subfamily C member 22;
GN   Name=DNAJC22;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May function as a co-chaperone.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; CR858714; CAH90923.1; -; mRNA.
DR   RefSeq; NP_001127351.1; NM_001133879.1.
DR   AlphaFoldDB; Q5RBD7; -.
DR   SMR; Q5RBD7; -.
DR   STRING; 9601.ENSPPYP00000005121; -.
DR   GeneID; 100174415; -.
DR   KEGG; pon:100174415; -.
DR   CTD; 79962; -.
DR   eggNOG; KOG0714; Eukaryota.
DR   InParanoid; Q5RBD7; -.
DR   OrthoDB; 1058581at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd06257; DnaJ; 1.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR036869; J_dom_sf.
DR   InterPro; IPR007829; TM2.
DR   Pfam; PF00226; DnaJ; 1.
DR   Pfam; PF05154; TM2; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; SSF46565; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..341
FT                   /note="DnaJ homolog subfamily C member 22"
FT                   /id="PRO_0000325864"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          277..341
FT                   /note="J"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
SQ   SEQUENCE   341 AA;  38119 MW;  F1BD6B61CCEB6B22 CRC64;
     MAKGLLVTYA LWAVGGPAGL HHLYLGRDSH ALLWMLTLGG GGLGWLWEFW KLPSFVAQAN
     RAQGQRQSPR GVTPPLSPIR FAAQVIVGIY FGLVALISLS SMVNFYIVAL PLAVGLGVLL
     VAAVGNQTSD FKNTLGAAFL TSPIFYGRPI AILPISVAAS ITAQKRRRYK ALVASEPLSV
     RLYRLGLAYL AFTGPLAYSA LCNTAATLSY VAETFGSFLN WFSFFPLLGR LMEFVLLLPY
     RIWRLLMGET GFNSSYFQEW AKLYEFVHSF QDEKRQLAYQ VLGLSEGATN EEIHRSYREL
     VKVWHPDHNL DQTEEAQRHF LEIQAAYEVL SQPRKPRGSR R