ID   DJC22_RAT               Reviewed;         341 AA.
AC   Q5PR00;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=DnaJ homolog subfamily C member 22;
GN   Name=Dnajc22;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Liver;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May function as a co-chaperone.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC086949; AAH86949.1; -; mRNA.
DR   RefSeq; NP_001014226.1; NM_001014204.1.
DR   RefSeq; XP_006257425.1; XM_006257363.3.
DR   AlphaFoldDB; Q5PR00; -.
DR   SMR; Q5PR00; -.
DR   STRING; 10116.ENSRNOP00000021339; -.
DR   PaxDb; Q5PR00; -.
DR   Ensembl; ENSRNOT00000087932; ENSRNOP00000073678; ENSRNOG00000053498.
DR   GeneID; 362998; -.
DR   KEGG; rno:362998; -.
DR   CTD; 79962; -.
DR   RGD; 1311098; Dnajc22.
DR   eggNOG; KOG0714; Eukaryota.
DR   GeneTree; ENSGT00390000012136; -.
DR   HOGENOM; CLU_057927_1_0_1; -.
DR   InParanoid; Q5PR00; -.
DR   OMA; LASAWWT; -.
DR   OrthoDB; 1058581at2759; -.
DR   PhylomeDB; Q5PR00; -.
DR   TreeFam; TF324581; -.
DR   PRO; PR:Q5PR00; -.
DR   Proteomes; UP000002494; Chromosome 7.
DR   Bgee; ENSRNOG00000053498; Expressed in liver and 17 other tissues.
DR   Genevisible; Q5PR00; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   CDD; cd06257; DnaJ; 1.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR036869; J_dom_sf.
DR   InterPro; IPR007829; TM2.
DR   Pfam; PF00226; DnaJ; 1.
DR   Pfam; PF05154; TM2; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; SSF46565; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..341
FT                   /note="DnaJ homolog subfamily C member 22"
FT                   /id="PRO_0000325865"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        232..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          277..341
FT                   /note="J"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
SQ   SEQUENCE   341 AA;  38243 MW;  F50C24CF6F372245 CRC64;
     MAKGLLMTYA LWAFGGPVGL HHLYLGRDSH ALLWMLTLGG GGLGWLWEFW KLPSFVAQAN
     GVQSWKQRPE EERPPLSLLR FASQMVVGVY FGLVALISLS STANFYIVGL PLAVGLGVLL
     VAAVGNQTSD FKNTLGAAFL TSPVFYGRPI AILPISLAAS ITAQKHRRYK VSAVSETLSV
     RLYRVGLAYL AFTGPLAYST LYNTAATINY AAETLGSFLS WFNFFPLLGR LVESVLLLPC
     RIWWLLVGAP GFNSSQFQEW EKLYEFVDSF QDEKRQLAHQ VLGIPEGATN EEIHRSYRDL
     VKVWHPDHNR HQTEEAQRHF LEIQAAYEVL SQPKKPRASW R