ID   DJC22_XENTR             Reviewed;         340 AA.
AC   A9ULE9;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=DnaJ homolog subfamily C member 22;
GN   Name=dnajc22;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6; TISSUE=Liver;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May function as a co-chaperone.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC157230; AAI57231.1; -; mRNA.
DR   RefSeq; NP_001107370.1; NM_001113898.1.
DR   AlphaFoldDB; A9ULE9; -.
DR   SMR; A9ULE9; -.
DR   STRING; 8364.ENSXETP00000024450; -.
DR   PaxDb; A9ULE9; -.
DR   Ensembl; ENSXETT00000024450; ENSXETP00000024450; ENSXETG00000011192.
DR   GeneID; 100135195; -.
DR   KEGG; xtr:100135195; -.
DR   CTD; 79962; -.
DR   Xenbase; XB-GENE-5859098; dnajc22.
DR   eggNOG; KOG0714; Eukaryota.
DR   HOGENOM; CLU_057927_1_0_1; -.
DR   InParanoid; A9ULE9; -.
DR   OMA; FYLGRDS; -.
DR   OrthoDB; 1058581at2759; -.
DR   PhylomeDB; A9ULE9; -.
DR   TreeFam; TF324581; -.
DR   Proteomes; UP000008143; Chromosome 2.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000011192; Expressed in liver and 4 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   CDD; cd06257; DnaJ; 1.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR036869; J_dom_sf.
DR   InterPro; IPR007829; TM2.
DR   Pfam; PF00226; DnaJ; 1.
DR   Pfam; PF05154; TM2; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; SSF46565; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..340
FT                   /note="DnaJ homolog subfamily C member 22"
FT                   /id="PRO_0000325866"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          278..340
FT                   /note="J"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
SQ   SEQUENCE   340 AA;  38721 MW;  16788E3C81097E01 CRC64;
     MGKSLLAAYG LWALGGPLGL YHIYLGRDSH ALLWMLTLGG FGMGWMWDFW KIPIHVYKYN
     RQERKNIEVK EGEPPASPIR FIGQVATGIY FGIVAAIGLS FLSSFHMVVL PLAVALGVHL
     VATVGEQTSD LKNTLIAAFL TSPIFYGRAV SMIPISLTAS ITSQKHMRYR LQQEKQEKLS
     LRLYRIGLVY LAFTGPLAYS ALLNTSLTVS YVAGSIGSML EWLSIFPSIS ALVERLLLLP
     YRVWAVFSGG GVFRDHYFKE WEKIYEFVAT FQSEKEEMAC KVLGVNFKST MEEINRKYRE
     LVKIWHPDHN RHRLEEAQEH FLEIQAAYET LMRLRKSKTL