ID   DJC25_XENTR             Reviewed;         368 AA.
AC   Q5HZT9;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=DnaJ homolog subfamily C member 25;
GN   Name=dnajc25;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DNAJC25 family. {ECO:0000305}.
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DR   EMBL; BC088889; AAH88889.1; -; mRNA.
DR   RefSeq; NP_001011497.1; NM_001011497.2.
DR   AlphaFoldDB; Q5HZT9; -.
DR   SMR; Q5HZT9; -.
DR   Ensembl; ENSXETT00000022541; ENSXETP00000022541; ENSXETG00000010217.
DR   GeneID; 496999; -.
DR   KEGG; xtr:496999; -.
DR   CTD; 548645; -.
DR   Xenbase; XB-GENE-954361; dnajc25.
DR   InParanoid; Q5HZT9; -.
DR   OrthoDB; 1332758at2759; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000010217; Expressed in heart and 15 other tissues.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   CDD; cd06257; DnaJ; 1.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR044632; DNAJC25-like.
DR   InterPro; IPR036869; J_dom_sf.
DR   PANTHER; PTHR44176; PTHR44176; 1.
DR   Pfam; PF00226; DnaJ; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; SSF46565; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..368
FT                   /note="DnaJ homolog subfamily C member 25"
FT                   /id="PRO_0000348573"
FT   TRANSMEM        25..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          57..132
FT                   /note="J"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
SQ   SEQUENCE   368 AA;  43755 MW;  6D975C07C80CE14D CRC64;
     MAALGKAEES QGCFGLFLLL PGPSMQPRLF VLVALSVLLL SGRAGALTEG LYCGRQVCYD
     VLGVSRDASK GDIARAYRQL ARKYHPDRYR PGEPPGPDGE TRESAQEKFL LVATAYETLK
     DEETRKDYDY MLDHPEEYYR HYYHYYSRRL APKVDVRIVI LVSVCAISIF QYYSWWSSYN
     EAINYLATVT KYRIQAMEIA KQQGLLNRTK EKGKNRRSKE EIKSEEEEII RDIIKNKIDI
     KGGYQKPQIF DILLFQIILF PYYIFKYISW YVHWIYTFNI QGKEYGEEEK LYLIRRNMKM
     SQSQFDTLEE HRKNSFLEQK LWIKENYEVY KLEQEEEMKK KMASDPRWKR YRRWMKNEGP
     GRLTFADD