ID   DLP3_ORNAN              Reviewed;          38 AA.
AC   P82141;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Defensin-like peptide 3 {ECO:0000303|PubMed:10417345};
DE            Short=DLP-3 {ECO:0000303|PubMed:10417345};
OS   Ornithorhynchus anatinus (Duckbill platypus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX   NCBI_TaxID=9258;
RN   [1]
RP   PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC   TISSUE=Venom, and Venom gland;
RX   PubMed=10417345; DOI=10.1042/bj3410785;
RA   Torres A.M., Wang X., Fletcher J.I., Alewood D., Alewood P.F., Smith R.,
RA   Simpson R.J., Nicholson G.M., Sutherland S.K., Gallagher C.H., King G.F.,
RA   Kuchel P.W.;
RT   "Solution structure of a defensin-like peptide from platypus venom.";
RL   Biochem. J. 341:785-794(1999).
CC   -!- FUNCTION: Does not show antimicrobial, myotoxic, hemolytic and cell-
CC       promoting activities. {ECO:0000269|PubMed:10417345}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10417345}.
CC   -!- TISSUE SPECIFICITY: Produced by the crural gland and detected in venom
CC       from the spur located on each male hind leg.
CC       {ECO:0000269|PubMed:10417345}.
CC   -!- WEB RESOURCE: Name=Protein Spotlight; Note=Platypus poison - Issue 29
CC       of December 2002;
CC       URL="https://web.expasy.org/spotlight/back_issues/029";
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DR   AlphaFoldDB; P82141; -.
DR   SMR; P82141; -.
DR   Proteomes; UP000002279; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.20.20.10; -; 1.
DR   InterPro; IPR012553; Defensin_3.
DR   InterPro; IPR023355; Myo_ane_neurotoxin_sf.
DR   Pfam; PF08131; Defensin_3; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Reference proteome; Secreted;
KW   Toxin.
FT   PEPTIDE         1..38
FT                   /note="Defensin-like peptide 3"
FT                   /evidence="ECO:0000269|PubMed:10417345"
FT                   /id="PRO_0000044773"
FT   DISULFID        6..36
FT                   /evidence="ECO:0000250|UniProtKB:P82140"
FT   DISULFID        13..29
FT                   /evidence="ECO:0000250|UniProtKB:P82140"
SQ   SEQUENCE   38 AA;  4721 MW;  4B2D1C6BB407F3DF CRC64;
     FEMQYCWSHS GVCRDKSERN NKPMAWTYCE NRQKKCEF