ID   DLP_SCHMA               Reviewed;          27 AA.
AC   P83914;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 29.
DE   RecName: Full=Dermaseptin-like peptide;
DE   AltName: Full=SmDLP;
OS   Schistosoma mansoni (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6183;
RN   [1]
RP   PROTEIN SEQUENCE, FUNCTION, AND MASS SPECTROMETRY.
RC   STRAIN=Puerto Rican; TISSUE=Larva;
RX   PubMed=16539015; DOI=10.1645/ge-540r.1;
RA   Quinn G.A., Heymans R., Rondaj F., Shaw C., de Jong-Brink M.;
RT   "Schistosoma mansoni dermaseptin-like peptide: structural and functional
RT   characterization.";
RL   J. Parasitol. 91:1340-1351(2005).
CC   -!- FUNCTION: Has antimicrobial activity against the Gram-positive
CC       bacterium M.luteus and the yeast C.albicans. Has hemolytic activity on
CC       human and duck erythrocytes. {ECO:0000269|PubMed:16539015}.
CC   -!- MASS SPECTROMETRY: Mass=2789; Mass_error=1; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:16539015};
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DR   AlphaFoldDB; P83914; -.
DR   Proteomes; UP000008854; Unassembled WGS sequence.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0044179; P:hemolysis in another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR022731; Dermaseptin.
DR   Pfam; PF12121; DD_K; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Cytolysis; Direct protein sequencing; Fungicide;
KW   Hemolysis; Reference proteome.
FT   PEPTIDE         1..27
FT                   /note="Dermaseptin-like peptide"
FT                   /id="PRO_0000044132"
SQ   SEQUENCE   27 AA;  2789 MW;  9AEFD4EB257FDC12 CRC64;
     DLWNSIKDMA AAAGRAALNA VTGMVNQ