ID   DLT1_CANGA              Reviewed;         389 AA.
AC   Q6FN06;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Defect at low temperature protein 1;
GN   Name=DLT1; OrderedLocusNames=CAGL0K03751g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for growth under high-pressure and low-temperature
CC       conditions. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DLT1 family. {ECO:0000305}.
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DR   EMBL; CR380957; CAG61349.1; -; Genomic_DNA.
DR   RefSeq; XP_448388.1; XM_448388.1.
DR   AlphaFoldDB; Q6FN06; -.
DR   STRING; 5478.XP_448388.1; -.
DR   EnsemblFungi; CAG61349; CAG61349; CAGL0K03751g.
DR   GeneID; 2890138; -.
DR   KEGG; cgr:CAGL0K03751g; -.
DR   CGD; CAL0134465; CAGL0K03751g.
DR   VEuPathDB; FungiDB:CAGL0K03751g; -.
DR   eggNOG; ENOG502RAJJ; Eukaryota.
DR   HOGENOM; CLU_066044_0_0_1; -.
DR   InParanoid; Q6FN06; -.
DR   OMA; YVIRRNS; -.
DR   Proteomes; UP000002428; Chromosome K.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR038869; DLT1.
DR   PANTHER; PTHR40021; PTHR40021; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..389
FT                   /note="Defect at low temperature protein 1"
FT                   /id="PRO_0000399020"
FT   TOPO_DOM        1..17
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        39..49
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        71..389
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   389 AA;  44572 MW;  CFA884AEFAA1866A CRC64;
     MILQEQRRLR LWLYKSSLFI SVLFLIGFSI VLPVDSIVQA IQSENNGFNT IIVIGSLAVF
     FVAAVTILIG RMLLHKSCLK DIPRRYIPVT NADLPHKSSR KMVIHNMERS KKLSGLFKTP
     KDPVIHPGLE PPARCDDPNT PKILPEYLNY KICIKSATDR LKYYGLFLNS ASDDVKSSQT
     FTDLVKSQFI KGNHNKRQVQ RAKDFIELYE RIRFSGDEVS RSEFIQFAEN CIYFSDLMIT
     MDITKVGLGN ISTRSQLSFN IAGSSVDRKL RKLNTARSNQ ISRLSSGQYP DITAFRYDTS
     NSDYHRQETD EDDFALDDMD YFPSVPPYMI RRNSTNTVSM RIPTSNSDDQ YNLGFNEIGD
     EDIQNNDQIR RYMSNTSKTD SFKTVIHNG