ID   DLT1_YEAS1              Reviewed;         342 AA.
AC   B3LM17;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Defect at low temperature protein 1;
GN   Name=DLT1; ORFNames=SCRG_02016;
OS   Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=285006;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM11-1a;
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA   Kruglyak L.;
RT   "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for growth under high-pressure and low-temperature
CC       conditions. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DLT1 family. {ECO:0000305}.
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DR   EMBL; CH408047; EDV11620.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3LM17; -.
DR   EnsemblFungi; EDV11620; EDV11620; SCRG_02016.
DR   HOGENOM; CLU_066044_0_0_1; -.
DR   Proteomes; UP000008335; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR038869; DLT1.
DR   PANTHER; PTHR40021; PTHR40021; 1.
PE   3: Inferred from homology;
KW   Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..342
FT                   /note="Defect at low temperature protein 1"
FT                   /id="PRO_0000399024"
FT   TOPO_DOM        1..15
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        37..47
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        69..342
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   342 AA;  39187 MW;  C9E6D8726929D3A0 CRC64;
     MSGFAKLKSW LYKASLFVSL ILLIGFSVVL PIDSIAQASK SENNAFNTFI VVGALVVFGV
     FCIFIIIGRM LFHKSCLKDI PRRYIPITPA DLPHRSSREA VLQNMERSKE LTILLKKPKD
     PVIHDGLEPP RRCDYPLDEK LFPEYLNYAD CIKSLTDRLK YHGLFLNNLD VRMNLEDTFA
     DVVNSQFVNH NANKIQLEKA KEFIDLYETI RFSGKDVTRD QFIKFVKFCL YFGEVSLTRD
     TSFANLHNFR LNGSSNNIGR TESKYSINPF DENEYAQDDM HYFPEPPTHL VRESSISTVA
     RHVSSGVDLT NSEEHPLDTD SDCNALRLKL SKADSYRSVI RH