ID   DLT1_YEAS7              Reviewed;         342 AA.
AC   A6ZMI6;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Defect at low temperature protein 1;
GN   Name=DLT1; ORFNames=SCY_4302;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Required for growth under high-pressure and low-temperature
CC       conditions. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DLT1 family. {ECO:0000305}.
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DR   EMBL; AAFW02000021; EDN64060.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZMI6; -.
DR   EnsemblFungi; EDN64060; EDN64060; SCY_4302.
DR   HOGENOM; CLU_066044_0_0_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR038869; DLT1.
DR   PANTHER; PTHR40021; PTHR40021; 1.
PE   3: Inferred from homology;
KW   Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..342
FT                   /note="Defect at low temperature protein 1"
FT                   /id="PRO_0000399026"
FT   TOPO_DOM        1..15
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        37..47
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        69..342
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   342 AA;  39159 MW;  1DC08C4271A0CB31 CRC64;
     MSGFAKLKSW LYKASLFVSL ILLIGFSVVL PIDSIAQASK SENNAFNTFI VVGALVVFGV
     FCIFIIIGRM LFHKSCLKDI PRRYIPITPA DLPHRSSREA VLQNMERSKE LTILLKKPKD
     PVIHDGLEPP RRCDYPLDEK LFPEYLNYAD CIKSLTDRLK YHGLFLNNLD VRMNLEDTFA
     DVVNSQFVNH NANKIQLEKA KEFIDLYETI RFSGKDVTRD QFIKFVKFCL YFGEVSLTRD
     TSFANLHNFK LNGSSNNIGR TESKYSINPF DENEYAQDDM HYFPEPPTHL VRESSISTVA
     RHVSSGVDLT NSEEHPLDTD SDCNALRLKL SKADSYRSVI RH