ID   DLT1_ZYGRC              Reviewed;         349 AA.
AC   C5DQ63;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Defect at low temperature protein 1;
GN   Name=DLT1; OrderedLocusNames=ZYRO0A08954g;
OS   Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS   / NRRL Y-229) (Candida mogii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX   NCBI_TaxID=559307;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC   Y-229;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Required for growth under high-pressure and low-temperature
CC       conditions. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DLT1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU928173; CAR25824.1; -; Genomic_DNA.
DR   RefSeq; XP_002494757.1; XM_002494712.1.
DR   AlphaFoldDB; C5DQ63; -.
DR   STRING; 559307.C5DQ63; -.
DR   PRIDE; C5DQ63; -.
DR   EnsemblFungi; CAR25824; CAR25824; ZYRO0A08954g.
DR   GeneID; 8201521; -.
DR   KEGG; zro:ZYRO0A08954g; -.
DR   HOGENOM; CLU_066044_0_0_1; -.
DR   InParanoid; C5DQ63; -.
DR   Proteomes; UP000008536; Chromosome A.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR038869; DLT1.
DR   PANTHER; PTHR40021; PTHR40021; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..349
FT                   /note="Defect at low temperature protein 1"
FT                   /id="PRO_0000399028"
FT   TOPO_DOM        1..18
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        40..49
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        71..349
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          312..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   349 AA;  40101 MW;  844A5F2EA3BF8630 CRC64;
     MPIIDFEIWK LWLFRSIKAI VIIFLVGFSI VLPVDSIVQA AESSNTALNT FIVVGALVAF
     GLVSIIIIVG RIIFCRSCIQ DIPRRYLPIT PNDLPHRGSR KMIMENMEKS KELSILFKKP
     KEPVIHAGLE PPSRCDDPRY EKLFPDYLNY RSCIKSLSDR LKYQGIFLNN MNIDMKLGET
     FADVVSNQFT RNTRNKTQID NSKKFIDLYE TIRYSGREVT RQQFIDFVSL AIYFVEVSLT
     RDDRSPALGE LNTGSQLQFN FDNGTWENDV SNYSFPNDAY SNGADYYYPE SINYLKRTNS
     TSTVARKVPS FVPTNPEEEH KMALDPQDPV SHKPSMHTLA DSFKYVTHR