DLTR_STRA3
ID DLTR_STRA3 Reviewed; 224 AA.
AC P0A4H9; Q8DXQ7; Q8E3C6; Q8VM69;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 98.
DE RecName: Full=Transcriptional regulatory protein DltR;
GN Name=dltR; OrderedLocusNames=gbs1835;
OS Streptococcus agalactiae serotype III (strain NEM316).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=211110;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=NEM316;
RX PubMed=11591677; DOI=10.1128/jb.183.21.6324-6334.2001;
RA Poyart C., Lamy M.C., Boumaila C., Fiedler F., Trieu-Cuot P.;
RT "Regulation of D-alanyl-lipoteichoic acid biosynthesis in Streptococcus
RT agalactiae involves a novel two-component regulatory system.";
RL J. Bacteriol. 183:6324-6334(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEM316;
RX PubMed=12354221; DOI=10.1046/j.1365-2958.2002.03126.x;
RA Glaser P., Rusniok C., Buchrieser C., Chevalier F., Frangeul L., Msadek T.,
RA Zouine M., Couve E., Lalioui L., Poyart C., Trieu-Cuot P., Kunst F.;
RT "Genome sequence of Streptococcus agalactiae, a pathogen causing invasive
RT neonatal disease.";
RL Mol. Microbiol. 45:1499-1513(2002).
CC -!- FUNCTION: Member of the two-component regulatory system DltS/DltR.
CC Regulates the expression of the dlt operon.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- PTM: Phosphorylated by DltS. {ECO:0000305}.
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DR EMBL; AJ291784; CAC83083.1; -; Genomic_DNA.
DR EMBL; AL766853; CAD47494.1; -; Genomic_DNA.
DR RefSeq; WP_001238594.1; NC_004368.1.
DR AlphaFoldDB; P0A4H9; -.
DR SMR; P0A4H9; -.
DR STRING; 211110.gbs1835; -.
DR EnsemblBacteria; CAD47494; CAD47494; CAD47494.
DR GeneID; 66886631; -.
DR KEGG; san:gbs1835; -.
DR eggNOG; COG0745; Bacteria.
DR HOGENOM; CLU_000445_30_1_9; -.
DR OMA; EDEKYMA; -.
DR Proteomes; UP000000823; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR039420; WalR-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR48111; PTHR48111; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Phosphoprotein; Transcription;
KW Transcription regulation; Two-component regulatory system.
FT CHAIN 1..224
FT /note="Transcriptional regulatory protein DltR"
FT /id="PRO_0000081066"
FT DOMAIN 2..116
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DNA_BIND 124..222
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01091"
FT MOD_RES 51
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 224 AA; 25504 MW; EB957DCA303D98B7 CRC64;
MRLLVVEDEK SIAEAIQALL ADKGYSVDLA FDGDDGLEYI LTGLYDLVLL DIMLPKRSGL
SVLKRVREAG LETPIIFLTA KSQTYDKVNG LDLGADDYIT KPFEADELLA RIRLRTRQSS
LIRANQLRLG NIRLNTDSHE LESKESSVKL SNKEFLLMEV FMRNAKQIIP KNQLISKVWG
PSDNSEYNQL EVFISFLRKK LRFLKADIEI ITTKGFGYSL EERT
