DM7A_DROME
ID DM7A_DROME Reviewed; 542 AA.
AC Q9W3L5; A9YJU0; A9YJU1; A9YJU2; A9YJU3; A9YJU7; A9YJU9; A9YJV0; Q8MTT0;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 3.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=DM7 family protein CG15333;
GN ORFNames=CG15333;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1] {ECO:0000312|EMBL:AAF46310.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2] {ECO:0000305, ECO:0000312|EMBL:AAF46310.3}
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [3] {ECO:0000305, ECO:0000312|EMBL:AAL68101.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-542.
RC STRAIN=Berkeley {ECO:0000269|PubMed:12537569};
RC TISSUE=Testis {ECO:0000269|PubMed:12537569};
RX PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA Celniker S.E.;
RT "A Drosophila full-length cDNA resource.";
RL Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
RN [4] {ECO:0000305, ECO:0000312|EMBL:ABW92931.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 189-412, AND VARIANTS GLU-252;
RP LYS-262; ASN-262; GLY-268 AND LYS-332.
RC STRAIN=ZW104 {ECO:0000312|EMBL:ABW92929.1},
RC ZW106 {ECO:0000312|EMBL:ABW92930.1}, ZW109 {ECO:0000312|EMBL:ABW92931.1},
RC ZW122 {ECO:0000312|EMBL:ABW92932.1}, ZW123 {ECO:0000312|EMBL:ABW92933.1},
RC ZW133 {ECO:0000312|EMBL:ABW92934.1}, ZW136 {ECO:0000312|EMBL:ABW92935.1},
RC ZW139 {ECO:0000312|EMBL:ABW92936.1}, ZW140 {ECO:0000312|EMBL:ABW92937.1},
RC ZW141 {ECO:0000312|EMBL:ABW92938.1}, ZW142 {ECO:0000312|EMBL:ABW92939.1},
RC and ZW143 {ECO:0000312|EMBL:ABW92940.1};
RX PubMed=17989248; DOI=10.1101/gr.6691007;
RA Andolfatto P.;
RT "Hitchhiking effects of recurrent beneficial amino acid substitutions in
RT the Drosophila melanogaster genome.";
RL Genome Res. 17:1755-1762(2007).
CC -!- SIMILARITY: Belongs to the DM7 family. {ECO:0000255}.
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DR EMBL; AE014298; AAF46310.3; -; Genomic_DNA.
DR EMBL; AY075234; AAL68101.2; -; mRNA.
DR EMBL; EU218023; ABW92929.1; -; Genomic_DNA.
DR EMBL; EU218024; ABW92930.1; -; Genomic_DNA.
DR EMBL; EU218025; ABW92931.1; -; Genomic_DNA.
DR EMBL; EU218026; ABW92932.1; -; Genomic_DNA.
DR EMBL; EU218027; ABW92933.1; -; Genomic_DNA.
DR EMBL; EU218028; ABW92934.1; -; Genomic_DNA.
DR EMBL; EU218029; ABW92935.1; -; Genomic_DNA.
DR EMBL; EU218030; ABW92936.1; -; Genomic_DNA.
DR EMBL; EU218031; ABW92937.1; -; Genomic_DNA.
DR EMBL; EU218032; ABW92938.1; -; Genomic_DNA.
DR EMBL; EU218033; ABW92939.1; -; Genomic_DNA.
DR EMBL; EU218034; ABW92940.1; -; Genomic_DNA.
DR RefSeq; NP_572431.2; NM_132203.4.
DR AlphaFoldDB; Q9W3L5; -.
DR SMR; Q9W3L5; -.
DR IntAct; Q9W3L5; 1.
DR STRING; 7227.FBpp0071076; -.
DR PaxDb; Q9W3L5; -.
DR PRIDE; Q9W3L5; -.
DR EnsemblMetazoa; FBtr0071124; FBpp0071076; FBgn0029989.
DR GeneID; 31720; -.
DR KEGG; dme:Dmel_CG15333; -.
DR UCSC; CG15333-RA; d. melanogaster.
DR FlyBase; FBgn0029989; CG15333.
DR VEuPathDB; VectorBase:FBgn0029989; -.
DR eggNOG; ENOG502QRB1; Eukaryota.
DR GeneTree; ENSGT00540000073740; -.
DR HOGENOM; CLU_477581_0_0_1; -.
DR InParanoid; Q9W3L5; -.
DR OMA; DNIAMAM; -.
DR OrthoDB; 1171145at2759; -.
DR PhylomeDB; Q9W3L5; -.
DR BioGRID-ORCS; 31720; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 31720; -.
DR PRO; PR:Q9W3L5; -.
DR Proteomes; UP000000803; Chromosome X.
DR Bgee; FBgn0029989; Expressed in testis and 7 other tissues.
DR ExpressionAtlas; Q9W3L5; baseline and differential.
DR Genevisible; Q9W3L5; DM.
DR InterPro; IPR006610; DM7.
DR SMART; SM00688; DM7; 2.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat.
FT CHAIN 1..542
FT /note="DM7 family protein CG15333"
FT /id="PRO_0000378603"
FT VARIANT 252
FT /note="D -> E (in strain: ZW141 and ZW142)"
FT /evidence="ECO:0000269|PubMed:17989248"
FT VARIANT 262
FT /note="I -> K (in strain: ZW106 and ZW133)"
FT /evidence="ECO:0000269|PubMed:17989248"
FT VARIANT 262
FT /note="I -> N (in strain: ZW104, ZW141 and ZW143)"
FT /evidence="ECO:0000269|PubMed:17989248"
FT VARIANT 268
FT /note="C -> G (in strain: ZW104, ZW106, ZW122, ZW133,
FT ZW136, ZW139, ZW140, ZW141, ZW142 and ZW143)"
FT /evidence="ECO:0000269|PubMed:17989248"
FT VARIANT 332
FT /note="E -> K (in strain: ZW122 and ZW136)"
FT /evidence="ECO:0000269|PubMed:17989248"
SQ SEQUENCE 542 AA; 60747 MW; D4635166CE2E5405 CRC64;
MDTVHRDKDQ VVILKKANYL PYLVNLFIPK LFYPEKIVVA RLYLDVNKHD KQAAENFEGT
ETPCFDVPPS LFADKVPMDK IVFLPTSMLP MGFEAGGVFG PGILTRRSYP IDLKAAGHKG
QTPPLFVGLR MEVQPPTRVE SLLKKDGESQ PIQDTLMNWL HASNDLINGA QPKGQELRDE
FSLSMVFNLP IPPSPPSPYS YGRIPLQCNI YTPDLSNVLL LMSHQRDLTV AILSTVNNPH
VPSVAFATMG DDAECPKFEL PIGVFPICEG VNRPIFLPKR FMPKGFEAGC VIKPGTLSEL
WFMDYIGRFG PPQPQYNGSI TPPLFVGKIC REEPAVDMIK KIQFEIEKKA SDDAESKATL
AGVKPKFDIS ITKGFMVMET KEPKSPKGAY SVQNYDEAFD DGCIVRVVKK PATAEEATET
RERNEMCTVG DQSQELDKCS TEADQKYLSC FHVDSDIDNI AMAMARLGIA DMSLHADEEE
LCGIDGDNAL IQLRHVLEDR NQIRSHTDQL MQDHIFRMNR DRMLALRQPF TCFGCGIHEK
KQ
