ID   DML1_COCIM              Reviewed;         516 AA.
AC   Q1E2I3; J3KB46;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2013, sequence version 2.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Protein DML1;
GN   Name=DML1; ORFNames=CIMG_03230;
OS   Coccidioides immitis (strain RS) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=246410;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RS;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=RS;
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
CC   -!- FUNCTION: Involved in the partitioning of the mitochondrial organelle
CC       and mitochondrial DNA (mtDNA) inheritance. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the misato family. {ECO:0000305}.
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DR   EMBL; GG704916; EAS32206.3; -; Genomic_DNA.
DR   RefSeq; XP_001243789.2; XM_001243788.2.
DR   AlphaFoldDB; Q1E2I3; -.
DR   STRING; 246410.Q1E2I3; -.
DR   EnsemblFungi; EAS32206; EAS32206; CIMG_03230.
DR   GeneID; 4564575; -.
DR   KEGG; cim:CIMG_03230; -.
DR   VEuPathDB; FungiDB:CIMG_03230; -.
DR   InParanoid; Q1E2I3; -.
DR   OMA; FGKKSIW; -.
DR   OrthoDB; 1321917at2759; -.
DR   Proteomes; UP000001261; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.1440; -; 1.
DR   InterPro; IPR029209; DML1/Misato_tubulin.
DR   InterPro; IPR019605; Misato_II_tubulin-like.
DR   InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR   Pfam; PF10644; Misat_Tub_SegII; 1.
DR   Pfam; PF14881; Tubulin_3; 1.
DR   SUPFAM; SSF52490; SSF52490; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..516
FT                   /note="Protein DML1"
FT                   /id="PRO_0000285333"
SQ   SEQUENCE   516 AA;  58758 MW;  63C2CB3B5AECC6A5 CRC64;
     MREIITLQLG QRSNYLATHF WNVQESYFTY SENEASPVDH DISFRPGIGA DGSETFTPRT
     IIYDLKGGFG SLRQYNALYE VEENVGMPKG LWDGNEVIQR QPNIPQSEYQ KALELGLPLP
     RLTPETVRYW SDFNRLFYHP KSIVQLNEYE MNSQLMPFED WTVGEAFFNS LDREHDLLDR
     DFRPFAEECD QLRGIQLFTG TDDAWGGFAA RYIDRLRDEF GKKIIWTFAL ESGLKTEREK
     QFLRAKNSAK SISEISRQST AYVPISMPPS KLPHYVNLNI ASEWYISALT SVAVESVTLP
     GRLRWYEGIE PWFLDNAGPQ RIFALRATIR SENSELPFAS HLRPNDSTQM DTDEVDHDEI
     EQSEQRFDLG FSPIGSATRT NNTHIFSQVQ VVRDSKCNSE RPERAEVGQG LTSHRLSLMT
     GYVPSTLSNF RSTLEFPILD SFPSDLIHEQ GPAGSTLRVD AALSATSGIG RDLKNLQQTI
     GRRIALEERE DLINGLHELS HAYQAGWEND SDSGDD