DML1_GIBZE
ID DML1_GIBZE Reviewed; 484 AA.
AC Q4IBL8; A0A0E0SLX9; V6RBJ1;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2005, sequence version 1.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Protein DML1;
GN Name=DML1; ORFNames=FGRRES_05390, FGSG_05390;
OS Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
OS / PH-1) (Wheat head blight fungus) (Fusarium graminearum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=229533;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=17823352; DOI=10.1126/science.1143708;
RA Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., Di Pietro A.,
RA Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., Antoniw J., Baldwin T.,
RA Calvo S.E., Chang Y.-L., DeCaprio D., Gale L.R., Gnerre S., Goswami R.S.,
RA Hammond-Kosack K., Harris L.J., Hilburn K., Kennell J.C., Kroken S.,
RA Magnuson J.K., Mannhaupt G., Mauceli E.W., Mewes H.-W., Mitterbauer R.,
RA Muehlbauer G., Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T.,
RA Qi W., Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT "The Fusarium graminearum genome reveals a link between localized
RT polymorphism and pathogen specialization.";
RL Science 317:1400-1402(2007).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.-J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.-B., Woloshuk C., Xie X., Xu J.-R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.J.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.-H., Li L., Manners J.M., Miranda-Saavedra D.,
RA Mukherjee M., Park G., Park J., Park S.-Y., Proctor R.H., Regev A.,
RA Ruiz-Roldan M.C., Sain D., Sakthikumar S., Sykes S., Schwartz D.C.,
RA Turgeon B.G., Wapinski I., Yoder O., Young S., Zeng Q., Zhou S.,
RA Galagan J., Cuomo C.A., Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA King R., Urban M., Hammond-Kosack M.C.U., Hassani-Pak K.,
RA Hammond-Kosack K.E.;
RT "The completed genome sequence of the pathogenic ascomycete fungus Fusarium
RT graminearum.";
RL BMC Genomics 16:544-544(2015).
CC -!- FUNCTION: Involved in the partitioning of the mitochondrial organelle
CC and mitochondrial DNA (mtDNA) inheritance. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the misato family. {ECO:0000305}.
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DR EMBL; DS231665; ESU11342.1; -; Genomic_DNA.
DR EMBL; HG970334; CEF87442.1; -; Genomic_DNA.
DR RefSeq; XP_011323918.1; XM_011325616.1.
DR AlphaFoldDB; Q4IBL8; -.
DR STRING; 5518.FGSG_05390P0; -.
DR EnsemblFungi; ESU11342; ESU11342; FGSG_05390.
DR GeneID; 23552574; -.
DR KEGG; fgr:FGSG_05390; -.
DR eggNOG; KOG2530; Eukaryota.
DR HOGENOM; CLU_022511_2_0_1; -.
DR InParanoid; Q4IBL8; -.
DR Proteomes; UP000070720; Chromosome 3.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.1440; -; 1.
DR InterPro; IPR029209; DML1/Misato_tubulin.
DR InterPro; IPR019605; Misato_II_tubulin-like.
DR InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR Pfam; PF10644; Misat_Tub_SegII; 1.
DR Pfam; PF14881; Tubulin_3; 1.
DR SUPFAM; SSF52490; SSF52490; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome.
FT CHAIN 1..484
FT /note="Protein DML1"
FT /id="PRO_0000285335"
SQ SEQUENCE 484 AA; 54320 MW; F0CDFC64C80E86EE CRC64;
MREIVTLQLD QESYFTYSSD EKSLIDHNVH WRAGLGADGS ETFLPRTVIY DLKGGFGSLR
KINALYEAES ESAPEALWSG QSVVHKQTPI TPSEYQQSLD AGSEPAQLTT SNVRYWSDFS
RVYFHPKSLN QLYDFELNST TMPFERFSMG TELFSMLDRE HDLADRDFRP FAEECDRMQG
IQVFTTIDDA WGGFTSSYLE SLRDDFPKTT IWTWGLQSPL LDISRAKRQL RLVNTAHSIE
QLCTQSTTVV PLALPEEDMT TSVSMDRRSP WHTSALMAAA IETATLPSRL TQGSSEQAGS
LDVLAESLNV NGNQPLASMR MSLAPAKDSP EDSRINVDFF QVGRVWSRQH VARLDTHKHV
FGEILSYRDL DPLGHDNENG HLAPGERPII GNSIVRKYDS ALRFPLLDAY PQIYPQLAGN
SDASLQTTLS TNSSIVQRIR TLRTESARLV PVNEREDLGN GLADLADAYQ EGWFSGSDED
DDDL