ID   DML1_KLULA              Reviewed;         468 AA.
AC   Q6CU61;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Protein DML1;
GN   Name=DML1; OrderedLocusNames=KLLA0C07381g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in the partitioning of the mitochondrial organelle
CC       and mitochondrial DNA (mtDNA) inheritance. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the misato family. {ECO:0000305}.
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DR   EMBL; CR382123; CAH01379.1; -; Genomic_DNA.
DR   RefSeq; XP_452528.1; XM_452528.1.
DR   AlphaFoldDB; Q6CU61; -.
DR   STRING; 28985.XP_452528.1; -.
DR   EnsemblFungi; CAH01379; CAH01379; KLLA0_C07381g.
DR   GeneID; 2891914; -.
DR   KEGG; kla:KLLA0_C07381g; -.
DR   eggNOG; KOG2530; Eukaryota.
DR   HOGENOM; CLU_022511_2_2_1; -.
DR   InParanoid; Q6CU61; -.
DR   OMA; DNGWGGF; -.
DR   Proteomes; UP000000598; Chromosome C.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IEA:EnsemblFungi.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:EnsemblFungi.
DR   Gene3D; 3.40.50.1440; -; 1.
DR   InterPro; IPR029209; DML1/Misato_tubulin.
DR   InterPro; IPR019605; Misato_II_tubulin-like.
DR   InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR   Pfam; PF10644; Misat_Tub_SegII; 1.
DR   Pfam; PF14881; Tubulin_3; 1.
DR   SUPFAM; SSF52490; SSF52490; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..468
FT                   /note="Protein DML1"
FT                   /id="PRO_0000285336"
SQ   SEQUENCE   468 AA;  54216 MW;  AC10C5B8CFA22FEE CRC64;
     MREIINVSVS HRSNHLITQF YNCLEPLLHD ADQENDVFLN PNIDKVSKTV SYTPRALLWD
     AKLGNGSLGT YQYVSENDYA DTLDSEQGAT AKTAHRVQTH DRIRKSPYQL ALDQGATVLP
     KINDEIAKYW SDYSKLIYDP SSFNTLQDWY HDAANQQKAP NFQNLRQVYF DNYETGSNQF
     RENYSNEFFD SNLHQQLEKC DSLQGFNIIT ELDNGWGGFS SSMLLELKDE LPKVSYHTYG
     WNQDDVCSLK EPVHSTKTKF QMLCNKIRAT IALSQESDLF FPLYANTKEA FWRSTGETVL
     LFDSVNSVFH GSRKQAATNS NMRKMSHLTN ALTLGESKRN IVSKLNVDEY NSFSFYDRMP
     LYKNSKKPSH TFTQCEIDRV NHKESSMFHF TTYPWTNSDT IPDTHHSCAE SVIGVTEKPR
     DVLKTWEDLV SRYFRYDSDR EEIKDHLGTL SLEYEHGWYD DDDSDLDL