ID   DML1_NEUCR              Reviewed;         540 AA.
AC   Q7S2Y8;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 2.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Protein dml-1;
GN   Name=dml-1; ORFNames=NCU08981, NCU11398;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- FUNCTION: Involved in the partitioning of the mitochondrial organelle
CC       and mitochondrial DNA (mtDNA) inheritance. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the misato family. {ECO:0000305}.
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DR   EMBL; CM002238; EAA29773.2; -; Genomic_DNA.
DR   RefSeq; XP_959009.2; XM_953916.3.
DR   AlphaFoldDB; Q7S2Y8; -.
DR   STRING; 5141.EFNCRP00000008954; -.
DR   EnsemblFungi; EAA29773; EAA29773; NCU08981.
DR   GeneID; 23568500; -.
DR   KEGG; ncr:NCU08981; -.
DR   VEuPathDB; FungiDB:NCU08981; -.
DR   HOGENOM; CLU_022511_2_0_1; -.
DR   InParanoid; Q7S2Y8; -.
DR   OMA; FGKKSIW; -.
DR   Proteomes; UP000001805; Chromosome 3, Linkage Group III.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0048311; P:mitochondrion distribution; IBA:GO_Central.
DR   Gene3D; 3.40.50.1440; -; 1.
DR   InterPro; IPR029209; DML1/Misato_tubulin.
DR   InterPro; IPR019605; Misato_II_tubulin-like.
DR   InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR   Pfam; PF10644; Misat_Tub_SegII; 1.
DR   Pfam; PF14881; Tubulin_3; 1.
DR   SUPFAM; SSF52490; SSF52490; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..540
FT                   /note="Protein dml-1"
FT                   /id="PRO_0000285338"
FT   REGION          517..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        517..533
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   540 AA;  60881 MW;  B0FEB5C38DAE6A5A CRC64;
     MHEIITLQLG QQSNYLATHF WNAQESYFTY SEDQEPAVNH DIHWRPGIGA DGTETYMPRT
     VIYDLKGGFG SMAKTNALYN DLEEGQTPQA LWNGPTVLQK QPAIPQSAYQ QSLDAGLEPP
     PLTTDTVRYW SDFNRVFYHP RSVVQLNEYE LNSSIMPFER YATGEDLFAS LDKEHDLLDR
     DLRPFIEEAD QMQGIQVMTG LDDAWGGFAA KYLERIRDEY GKTAMFVWGS EQESVMRAGG
     LSREKRLLRL ANKARTMTEV YKYASVVVPF TVPATLPGSV VLDAGSQWHN TALSAAAIES
     VTLPSRLRDP ANRDTMATLA DSLNAMGKQN VASLGMSFAP EPTEEEDVVM EGTQDFRQRQ
     LLNQKSSRHA AVMVKENPEG VFLDINFTPT DQLDYVRRRG GGDDDRPRVF SQMLTSRGYE
     IDEQVQEAKE AEEDERFRRR SSYETVMKSY HTPLRFPLLD SFPQIFRDDS GEPLKRGGAI
     NVTSSLSTDA SVHKRLKSLR TTVGRSIGLE DREQLGNELA EMADEYHEGW SSGSDDGDDD