DMP7_ARATH
ID DMP7_ARATH Reviewed; 200 AA.
AC Q5XV67; F4JLA4; Q4PSH9;
DT 27-SEP-2017, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Protein DMP7 {ECO:0000303|PubMed:20712629};
DE Short=AtDMP7 {ECO:0000303|PubMed:20712629};
GN Name=DMP7 {ECO:0000303|PubMed:20712629};
GN OrderedLocusNames=At4g28485 {ECO:0000312|Araport:AT4G28485};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=16244158; DOI=10.1104/pp.105.063479;
RA Xiao Y.-L., Smith S.R., Ishmael N., Redman J.C., Kumar N., Monaghan E.L.,
RA Ayele M., Haas B.J., Wu H.C., Town C.D.;
RT "Analysis of the cDNAs of hypothetical genes on Arabidopsis chromosome 2
RT reveals numerous transcript variants.";
RL Plant Physiol. 139:1323-1337(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [5]
RP TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, SUBCELLULAR LOCATION, GENE FAMILY,
RP AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=20712629; DOI=10.1111/j.1438-8677.2010.00381.x;
RA Kasaras A., Kunze R.;
RT "Expression, localisation and phylogeny of a novel family of plant-specific
RT membrane proteins.";
RL Plant Biol. 12 Suppl. 1:140-152(2010).
CC -!- FUNCTION: Involved in membrane remodeling.
CC {ECO:0000250|UniProtKB:Q9LVF4}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:20712629}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5XV67-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5XV67-2; Sequence=VSP_059069;
CC -!- TISSUE SPECIFICITY: Expressed in leaves, stems, flowers, siliques and
CC roots, especially in the vasculature. {ECO:0000269|PubMed:20712629}.
CC -!- DEVELOPMENTAL STAGE: Accumulates in tissues undergoing dehiscence and
CC abscission. {ECO:0000269|PubMed:20712629}.
CC -!- SIMILARITY: Belongs to the plant DMP1 protein family. {ECO:0000305}.
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DR EMBL; AL161572; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002687; AEE85493.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM66465.1; -; Genomic_DNA.
DR EMBL; AY735655; AAU44525.1; -; mRNA.
DR EMBL; DQ056657; AAY78804.1; -; mRNA.
DR RefSeq; NP_001328357.1; NM_001341919.1. [Q5XV67-1]
DR RefSeq; NP_680746.1; NM_148380.2. [Q5XV67-2]
DR AlphaFoldDB; Q5XV67; -.
DR iPTMnet; Q5XV67; -.
DR PRIDE; Q5XV67; -.
DR EnsemblPlants; AT4G28485.1; AT4G28485.1; AT4G28485. [Q5XV67-2]
DR EnsemblPlants; AT4G28485.2; AT4G28485.2; AT4G28485. [Q5XV67-1]
DR GeneID; 828966; -.
DR Gramene; AT4G28485.1; AT4G28485.1; AT4G28485. [Q5XV67-2]
DR Gramene; AT4G28485.2; AT4G28485.2; AT4G28485. [Q5XV67-1]
DR KEGG; ath:AT4G28485; -.
DR Araport; AT4G28485; -.
DR TAIR; locus:504955516; AT4G28485.
DR OMA; VNCFYPK; -.
DR OrthoDB; 1350049at2759; -.
DR PhylomeDB; Q5XV67; -.
DR PRO; PR:Q5XV67; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q5XV67; baseline and differential.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009838; P:abscission; IEP:UniProtKB.
DR GO; GO:0009900; P:dehiscence; IEP:UniProtKB.
DR GO; GO:0010256; P:endomembrane system organization; ISS:UniProtKB.
DR InterPro; IPR007770; DMP.
DR PANTHER; PTHR31621; PTHR31621; 1.
DR Pfam; PF05078; DUF679; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Endoplasmic reticulum; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..200
FT /note="Protein DMP7"
FT /evidence="ECO:0000255"
FT /id="PRO_0000441614"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000255"
FT VAR_SEQ 28..98
FT /note="RKTFKGTAHLSNLLPTGSVMSFQIMCPVLTHQGQCPTITSRWLTCFLVSLCA
FT ISCFLFSFTDSIRDPNGKV -> SVPPSPVAGSPASSSPYAPSPASSSPLPTPLETQTA
FT (in isoform 2)"
FT /id="VSP_059069"
FT CONFLICT 199
FT /note="K -> Q (in Ref. 4; AAY78804)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 200 AA; 22318 MW; 1607271BF6B1DB48 CRC64;
MEETKQSLIA SLPSAPRKPK SKVERVVRKT FKGTAHLSNL LPTGSVMSFQ IMCPVLTHQG
QCPTITSRWL TCFLVSLCAI SCFLFSFTDS IRDPNGKVRY GLATWSGLLV MDGSITLTEE
EKEKYKLKIL DFIHAIMSML VFFAVSMFDQ NVTRCLFPVP SEETKEILTS LPFVIGVICG
AFFLAFPTRR HGIGSPLTKE
