ID   DMPH_PSEUF              Reviewed;         264 AA.
AC   P49156;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=4-oxalocrotonate decarboxylase;
DE            Short=4-OD;
DE            EC=4.1.1.77;
GN   Name=dmpH;
OS   Pseudomonas sp. (strain CF600).
OG   Plasmid pVI150.
OC   Bacteria; Proteobacteria.
OX   NCBI_TaxID=79676;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1732207; DOI=10.1128/jb.174.3.711-724.1992;
RA   Shingler V., Marklund U., Powlowski J.;
RT   "Nucleotide sequence and functional analysis of the complete phenol/3,4-
RT   dimethylphenol catabolic pathway of Pseudomonas sp. strain CF600.";
RL   J. Bacteriol. 174:711-724(1992).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(3E)-2-oxohex-3-enedioate + H(+) = 2-oxopent-4-enoate + CO2;
CC         Xref=Rhea:RHEA:24260, ChEBI:CHEBI:11641, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:64908; EC=4.1.1.77;
CC   -!- PATHWAY: Aromatic compound metabolism; benzoate degradation via
CC       hydroxylation.
CC   -!- SIMILARITY: Belongs to the hydratase/decarboxylase family.
CC       {ECO:0000305}.
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DR   EMBL; X60835; CAA43228.1; -; Genomic_DNA.
DR   AlphaFoldDB; P49156; -.
DR   SMR; P49156; -.
DR   KEGG; ag:CAA43228; -.
DR   UniPathway; UPA00156; -.
DR   GO; GO:0047437; F:4-oxalocrotonate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043640; P:benzoate catabolic process via hydroxylation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.90.850.10; -; 1.
DR   InterPro; IPR017630; 4-oxalocrotonate_decarboxylase.
DR   InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR   SUPFAM; SSF56529; SSF56529; 1.
DR   TIGRFAMs; TIGR03218; catechol_dmpH; 1.
PE   3: Inferred from homology;
KW   Aromatic hydrocarbons catabolism; Lyase; Plasmid.
FT   CHAIN           1..264
FT                   /note="4-oxalocrotonate decarboxylase"
FT                   /id="PRO_0000079939"
SQ   SEQUENCE   264 AA;  28427 MW;  518DB0C45C048FAE CRC64;
     MNRTLTRDQV LALAEHIENA ELDVHDIPKV TNDYPDMTFA DAYDVQWEIR RRKEARGNKV
     VGLKMGLTSW AKMAQMGVET PIYGFLVDYF SVPDGGVVDT SKLIHPKIEA EISFVTKAPL
     HGPGCHIGQV LAATDFVIPT VEVIDSRYEN FKFDLISVVA DNASSTRFIT GGQMANVADL
     DLRTLGVVME KNGEVVELGA GAAVLGHPAS SVAMLANLLA ERGEHIPAGS FIMTGGITAA
     VPVAPGDNIT VRYQGLCSVS ARFI