ID   DMRT1_ALLMI             Reviewed;         101 AA.
AC   Q9PUE0;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Doublesex- and mab-3-related transcription factor 1;
DE   Flags: Fragment;
GN   Name=DMRT1;
OS   Alligator mississippiensis (American alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=8496;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Embryonic testis;
RX   PubMed=10604464; DOI=10.1038/45130;
RA   Smith C.A., McClive P.J., Western P.S., Reed K.J., Sinclair A.H.;
RT   "Conservation of a sex-determining gene.";
RL   Nature 402:601-602(1999).
CC   -!- FUNCTION: May be required for testis development.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in the developing urogenital system
CC       (developmental stages 20 to 23) and later in the gonads (stages 24 to
CC       27) at both male- and female-producing temperatures, but up-regulated
CC       at the male-determining temperature. May be highly expressed in
CC       testicular differentiation and weakly expressed in ovarian
CC       differentiation.
CC   -!- SIMILARITY: Belongs to the DMRT family. {ECO:0000305}.
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DR   EMBL; AF192560; AAF03893.1; -; mRNA.
DR   AlphaFoldDB; Q9PUE0; -.
DR   SMR; Q9PUE0; -.
DR   STRING; 8496.XP_006261327.1; -.
DR   eggNOG; KOG3815; Eukaryota.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.
DR   InterPro; IPR026607; DMRT.
DR   InterPro; IPR022114; DMRT1-like.
DR   PANTHER; PTHR12322; PTHR12322; 1.
DR   Pfam; PF12374; Dmrt1; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Differentiation; DNA-binding; Metal-binding;
KW   Nucleus; Sexual differentiation; Transcription; Transcription regulation;
KW   Zinc.
FT   CHAIN           <1..>101
FT                   /note="Doublesex- and mab-3-related transcription factor 1"
FT                   /id="PRO_0000207046"
FT   DNA_BIND        <1..13
FT                   /note="DM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00070"
FT   REGION          52..79
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT   NON_TER         101
SQ   SEQUENCE   101 AA;  10786 MW;  856F8999F0A0980A CRC64;
     SLIAERQRVM AAQVALRRQQ AQEEELGISH PIPLPSATEL FVKKENSGGS SCLLLESSSP
     THSTSTVTTV STSPSEGRML IQDVPSITSR GHLESTSDLV V