ID   DMRT1_TRASC             Reviewed;         205 AA.
AC   P57690;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Doublesex- and mab-3-related transcription factor 1;
DE   Flags: Fragment;
GN   Name=DMRT1;
OS   Trachemys scripta (Red-eared slider turtle) (Pseudemys scripta).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Testudinoidea; Emydidae; Trachemys.
OX   NCBI_TaxID=34903;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Embryonic gonad;
RX   PubMed=10705377;
RX   DOI=10.1002/(sici)1526-968x(200003)26:3<174::aid-gene2>3.0.co;2-j;
RA   Kettlewell J.R., Raymond C.S., Zarkower D.;
RT   "Temperature-dependent expression of turtle Dmrt1 prior to sexual
RT   differentiation.";
RL   Genesis 26:174-178(2000).
CC   -!- FUNCTION: May be required for testis development.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
CC   -!- DEVELOPMENTAL STAGE: At stages 15, 17 and 20, expression is higher in
CC       the genital ridge/mesonephros complexes of embryos incubated at the
CC       male-promoting temperature. At female promoting temperature, weakly
CC       expressed in the genital ridge.
CC   -!- SIMILARITY: Belongs to the DMRT family. {ECO:0000305}.
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DR   EMBL; AF201387; AAF77096.1; -; mRNA.
DR   AlphaFoldDB; P57690; -.
DR   SMR; P57690; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.1040.10; -; 1.
DR   InterPro; IPR001275; DM_DNA-bd.
DR   InterPro; IPR036407; DM_DNA-bd_sf.
DR   InterPro; IPR026607; DMRT.
DR   InterPro; IPR022114; DMRT1-like.
DR   PANTHER; PTHR12322; PTHR12322; 2.
DR   Pfam; PF00751; DM; 1.
DR   Pfam; PF12374; Dmrt1; 1.
DR   SMART; SM00301; DM; 1.
DR   SUPFAM; SSF82927; SSF82927; 1.
DR   PROSITE; PS50809; DM_2; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Differentiation; DNA-binding; Metal-binding;
KW   Nucleus; Sexual differentiation; Transcription; Transcription regulation;
KW   Zinc.
FT   CHAIN           <1..>205
FT                   /note="Doublesex- and mab-3-related transcription factor 1"
FT                   /id="PRO_0000207047"
FT   DNA_BIND        <1..29
FT                   /note="DM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00070"
FT   REGION          180..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT   NON_TER         205
SQ   SEQUENCE   205 AA;  22807 MW;  4B3BBD9A697AC7B4 CRC64;
     GHKRFCMWRD CQCKKCSLIA ERQRVMAAQV ALRRQQAQEE ELGISHPIPL PSAPKLFVKK
     ENNGGSSCLL LESSSPTHST NTATTASTTP SEGRMLIQDI PSITSRGHLE STSDLVVDST
     YYSSFYQPSL YPYYNNLYNY SQYQMAVASD SSSSDMGGTL AGSPVKNSLR SLPATYMSSQ
     SGNQWQMKST ESRHAMSSQY RMHSY