DMRTD_BOVIN
ID DMRTD_BOVIN Reviewed; 370 AA.
AC Q32LE6;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Doublesex- and mab-3-related transcription factor C2;
GN Name=DMRTC2;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in sexual development. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
CC -!- SIMILARITY: Belongs to the DMRT family. {ECO:0000305}.
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DR EMBL; BC109620; AAI09621.1; -; mRNA.
DR RefSeq; NP_001033271.1; NM_001038182.2.
DR AlphaFoldDB; Q32LE6; -.
DR SMR; Q32LE6; -.
DR STRING; 9913.ENSBTAP00000025660; -.
DR PaxDb; Q32LE6; -.
DR PRIDE; Q32LE6; -.
DR GeneID; 539134; -.
DR KEGG; bta:539134; -.
DR CTD; 63946; -.
DR eggNOG; KOG3815; Eukaryota.
DR InParanoid; Q32LE6; -.
DR OrthoDB; 897429at2759; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.
DR Gene3D; 4.10.1040.10; -; 1.
DR InterPro; IPR001275; DM_DNA-bd.
DR InterPro; IPR036407; DM_DNA-bd_sf.
DR InterPro; IPR026607; DMRT.
DR InterPro; IPR031577; DMRT-C1/C2_C.
DR PANTHER; PTHR12322; PTHR12322; 1.
DR Pfam; PF00751; DM; 1.
DR Pfam; PF15791; DMRT-like; 1.
DR SMART; SM00301; DM; 1.
DR SUPFAM; SSF82927; SSF82927; 1.
DR PROSITE; PS40000; DM_1; 1.
DR PROSITE; PS50809; DM_2; 1.
PE 2: Evidence at transcript level;
KW Differentiation; DNA-binding; Metal-binding; Nucleus; Reference proteome;
KW Sexual differentiation; Transcription; Transcription regulation; Zinc.
FT CHAIN 1..370
FT /note="Doublesex- and mab-3-related transcription factor
FT C2"
FT /id="PRO_0000244105"
FT DNA_BIND 42..89
FT /note="DM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00070"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 103..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 370 AA; 39352 MW; 235E9D556255228D CRC64;
MDPSEMPAVH HCPSDSATGG ETRAPQGMEL IPRRAVRRSP TCARCRNHGV TAHLKGHKRL
CLFQACECHK CVLILERRRV MAAQVALRRQ QEAQLKRHLT QGLMRGAAPP RAPSRVKKGV
TQPGVHSGKE NIAPQPQIPH HVVPLALTSP GKENSRGPLL LSRPPEALPL PWTPMPPGPW
APGHWLPPGL SMPTPVVCRL LCQEPAIPLH PFPGFDPGTT LRLPTHGPLP TCTGSHPILT
APLSGESQGP STLPRTCSTL ILQPCGTPDP LLLQPQAPGP SRLTWTSASS EWQLQREAAE
ALVGLKDSSQ APRLTPGPAN PAWISLLHPC GPPAAAGGRG FQPVGPSLRP SPAPSVALHI
GRLGSISLLS