ID   DMSC_HALSA              Reviewed;         435 AA.
AC   Q9HR72;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Putative dimethyl sulfoxide reductase membrane subunit C;
DE            Short=DMSO reductase subunit C;
GN   Name=dmsC; Synonyms=moz; OrderedLocusNames=VNG_0831G;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
RN   [2]
RP   PUTATIVE FUNCTION, AND INDUCTION.
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=15716436; DOI=10.1128/jb.187.5.1659-1667.2005;
RA   Muller J.A., DasSarma S.;
RT   "Genomic analysis of anaerobic respiration in the archaeon Halobacterium
RT   sp. strain NRC-1: dimethyl sulfoxide and trimethylamine N-oxide as terminal
RT   electron acceptors.";
RL   J. Bacteriol. 187:1659-1667(2005).
CC   -!- FUNCTION: Dimethyl sulfoxide (DMSO) reductase catalyzes the reduction
CC       of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS) during anaerobic
CC       respiration; it can also use trimethylamine N-oxide (TMAO) as terminal
CC       electron acceptor. Subunit C is proposed to be a membrane anchoring
CC       subunit.
CC   -!- SUBUNIT: Probable multiprotein complex that likely consists of DmsA,
CC       DmsB and DmsC.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- INDUCTION: By anaerobic conditions. Its expression is under the control
CC       of DmsR. {ECO:0000269|PubMed:15716436}.
CC   -!- SIMILARITY: Belongs to the NrfD family. {ECO:0000305}.
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DR   EMBL; AE004437; AAG19286.1; -; Genomic_DNA.
DR   PIR; B84240; B84240.
DR   RefSeq; WP_010902582.1; NC_002607.1.
DR   AlphaFoldDB; Q9HR72; -.
DR   SMR; Q9HR72; -.
DR   STRING; 64091.VNG_0831G; -.
DR   TCDB; 5.A.3.3.3; the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.
DR   PaxDb; Q9HR72; -.
DR   EnsemblBacteria; AAG19286; AAG19286; VNG_0831G.
DR   GeneID; 5953699; -.
DR   KEGG; hal:VNG_0831G; -.
DR   PATRIC; fig|64091.14.peg.639; -.
DR   HOGENOM; CLU_021295_1_0_2; -.
DR   InParanoid; Q9HR72; -.
DR   OMA; WWVGIGH; -.
DR   OrthoDB; 14255at2157; -.
DR   PhylomeDB; Q9HR72; -.
DR   Proteomes; UP000000554; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR005614; NrfD_fam.
DR   Pfam; PF03916; NrfD; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..435
FT                   /note="Putative dimethyl sulfoxide reductase membrane
FT                   subunit C"
FT                   /id="PRO_0000428976"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        281..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        333..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        392..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   435 AA;  47053 MW;  3A82460DC0B4795C CRC64;
     MADDDTTARR PVLSSFGTLG RGWLGVLALL LVIGLGAWAY QLQHGLIETG MRNVFSWGLY
     IMLFVLFVGL SAGGLILSSA PKFFHSQRYE GFARLGVLVS LGCIIVAGLL ILPDIGRPDR
     IYQFVTSPDF RSPMVWDFGI VMLYGALNVW YLWLLTRRDL AARGSRLSLW VSDSAAGRDR
     DRTLMFWTAV CALPAAVALH SVTGWIFATQ VGRGDWFSPL VAPVFIAKAL VSGLGLLLVV
     SILADRFTAF TADRGELTSL GKLLGIFLAF HVVYLLAAER LPHAWAHHFG FWAITSNFLI
     GDTVYFWLWT GLGGAVPLLL LATPSLRRRT AVIFTASVLA VFGTLFEGIR LVFTGYQRVN
     INAAPGIATG GEYAGLTTDA WATAGTYTPT AVEIAVTVGV ISIGALIVMA GLRYLPLQRA
     APDAAYATDG GDRTQ