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DMSR_HALSA
ID   DMSR_HALSA              Reviewed;         224 AA.
AC   Q9HR76;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Dimethyl sulfoxide reductase transcriptional activator;
DE            Short=DMSO reductase transcriptional activator;
GN   Name=dmsR; OrderedLocusNames=VNG_0826C;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
RN   [2]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=15716436; DOI=10.1128/jb.187.5.1659-1667.2005;
RA   Muller J.A., DasSarma S.;
RT   "Genomic analysis of anaerobic respiration in the archaeon Halobacterium
RT   sp. strain NRC-1: dimethyl sulfoxide and trimethylamine N-oxide as terminal
RT   electron acceptors.";
RL   J. Bacteriol. 187:1659-1667(2005).
CC   -!- FUNCTION: Involved in activating dmsEABCD gene expression related to
CC       dimethyl sulfoxide (DMSO) reductase. Required for anaerobic respiration
CC       on dimethyl sulfoxide (DMSO) and trimethylamine N-oxide (TMAO).
CC       {ECO:0000269|PubMed:15716436}.
CC   -!- DISRUPTION PHENOTYPE: Cells lacking this gene displayed a marked
CC       decrease in growth under anaerobic conditions using either DMSO or TMAO
CC       as terminal electron acceptors. {ECO:0000269|PubMed:15716436}.
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DR   EMBL; AE004437; AAG19282.1; -; Genomic_DNA.
DR   PIR; F84239; F84239.
DR   RefSeq; WP_010902578.1; NC_002607.1.
DR   AlphaFoldDB; Q9HR76; -.
DR   STRING; 64091.VNG_0826C; -.
DR   PaxDb; Q9HR76; -.
DR   EnsemblBacteria; AAG19282; AAG19282; VNG_0826C.
DR   GeneID; 5953987; -.
DR   GeneID; 62884249; -.
DR   KEGG; hal:VNG_0826C; -.
DR   PATRIC; fig|64091.14.peg.635; -.
DR   HOGENOM; CLU_109670_1_0_2; -.
DR   OMA; AFSEVGC; -.
DR   OrthoDB; 70649at2157; -.
DR   PhylomeDB; Q9HR76; -.
DR   Proteomes; UP000000554; Chromosome.
DR   InterPro; IPR007050; HTH_bacterioopsin.
DR   Pfam; PF04967; HTH_10; 1.
PE   4: Predicted;
KW   Activator; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..224
FT                   /note="Dimethyl sulfoxide reductase transcriptional
FT                   activator"
FT                   /id="PRO_0000428979"
FT   DOMAIN          158..209
FT                   /note="HTH bat-type"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   224 AA;  23608 MW;  2996D5822C29A979 CRC64;
     MSERTASQPN TDRSRRRLRV VLDVALSDAA ACPLEEIDGE VTAVRHQYTG DDCHADVTVA
     PACPDDDRSD VMHVATQTTD SCLCCVFSDH GCVPQITAVA ADTITVETYL ADRTTLTDLV
     ADLKAVANTV SLTHLTRLAA DDQSGDSHTH VTLDLFKLTD KQREAAAAAV AKGYYATPRG
     ADLSDLATAL GISKSAVSQR LSAVESKLAT SAFTEAQQSA GSAP
 
 
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