ID   DMTA2_MONAL             Reviewed;         448 AA.
AC   A8TSS9;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Doublesex- and mab-3-related transcription factor A2;
DE   AltName: Full=Doublesex- and mab-3-related transcription factor 5;
GN   Name=dmrta2; Synonyms=dmrt5;
OS   Monopterus albus (Swamp eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Synbranchidae; Monopterus.
OX   NCBI_TaxID=43700;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Zhang L., Zhou R.;
RT   "Monopterus albus doublesex and mab-3 related factor 5.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in sexual development.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
CC   -!- SIMILARITY: Belongs to the DMRT family. {ECO:0000305}.
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DR   EMBL; EU053217; ABW06380.1; -; mRNA.
DR   AlphaFoldDB; A8TSS9; -.
DR   SMR; A8TSS9; -.
DR   STRING; 43700.ENSMALP00000023516; -.
DR   Proteomes; UP000261600; Whole Genome Shotgun Assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 4.10.1040.10; -; 1.
DR   InterPro; IPR001275; DM_DNA-bd.
DR   InterPro; IPR036407; DM_DNA-bd_sf.
DR   InterPro; IPR005173; DMA.
DR   InterPro; IPR026607; DMRT.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR12322; PTHR12322; 1.
DR   Pfam; PF00751; DM; 1.
DR   Pfam; PF03474; DMA; 1.
DR   SMART; SM00301; DM; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF82927; SSF82927; 1.
DR   PROSITE; PS40000; DM_1; 1.
DR   PROSITE; PS50809; DM_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Zinc.
FT   CHAIN           1..448
FT                   /note="Doublesex- and mab-3-related transcription factor
FT                   A2"
FT                   /id="PRO_0000333776"
FT   DOMAIN          259..294
FT                   /note="DMA"
FT                   /evidence="ECO:0000255"
FT   DNA_BIND        57..104
FT                   /note="DM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00070"
FT   REGION          166..259
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        166..191
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   448 AA;  47696 MW;  6E5356C006A2EBAA CRC64;
     MDLRPELPTA SSASQVHPGA AAAAAAASIP VSMAGNLLRG PPLLLRAADK YPRTPKCARC
     RNHGVVSALK GHKRYCRWKD CMCAKCTLIA ERQRVMAAQV ALRRQQAQEE NEARELQLLY
     GTAEGLALAA ANGIIPPRPN YEVFGSVNNE TNSDSSIPKY ELFSKSQLSG SATPQQSVGK
     PASTESDSAP GISSPEGRHG GSGSENGDSE SFISSPVSKP IKDGEETPGS VSSLGSDSGS
     ETDKDDQEPS PSSAASRHMN AIDILTRVFP SHKRSVQELV LQGCGKDVVR AIEQILNNSG
     AQGPNKTGPE ETWTAERMLQ NAQQLPQSSA STTTPTRPML PGAMTLSNRS AFSPLQPNAP
     HFGADPSTYP LGTPLGLNPL RLAYSAHSRG LAFMTPYSTT GLMPTLGFRP PMDYAFSDLI
     RDRTMLHKEQ GYASGLYGPL VNNTPDKQ