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DMTA2_ORYLA
ID   DMTA2_ORYLA             Reviewed;         416 AA.
AC   Q76L87;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Doublesex- and mab-3-related transcription factor A2;
DE   AltName: Full=Doublesex- and mab-3-related transcription factor 5;
DE            Short=Ola-DMRT5;
GN   Name=dmrta2; Synonyms=dmrt5;
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=8090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=HNI; TISSUE=Testis;
RA   Kitano A., Kondo M., Shima A.;
RT   "Molecular cloning and expression analysis of DMRT5 genes of the medaka
RT   Oryzias latipes.";
RL   Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in sexual development.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
CC   -!- SIMILARITY: Belongs to the DMRT family. {ECO:0000305}.
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DR   EMBL; AB083691; BAD00703.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q76L87; -.
DR   SMR; Q76L87; -.
DR   InParanoid; Q76L87; -.
DR   Proteomes; UP000001038; Unplaced.
DR   Proteomes; UP000265180; Chromosome 9.
DR   Proteomes; UP000265200; Chromosome 9.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0007548; P:sex differentiation; IBA:GO_Central.
DR   Gene3D; 4.10.1040.10; -; 1.
DR   InterPro; IPR001275; DM_DNA-bd.
DR   InterPro; IPR036407; DM_DNA-bd_sf.
DR   InterPro; IPR005173; DMA.
DR   InterPro; IPR026607; DMRT.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR12322; PTHR12322; 1.
DR   Pfam; PF00751; DM; 1.
DR   Pfam; PF03474; DMA; 1.
DR   SMART; SM00301; DM; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF82927; SSF82927; 1.
DR   PROSITE; PS40000; DM_1; 1.
DR   PROSITE; PS50809; DM_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Zinc.
FT   CHAIN           1..416
FT                   /note="Doublesex- and mab-3-related transcription factor
FT                   A2"
FT                   /id="PRO_0000333778"
FT   DOMAIN          228..263
FT                   /note="DMA"
FT                   /evidence="ECO:0000255"
FT   DNA_BIND        25..72
FT                   /note="DM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00070"
FT   REGION          133..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        133..158
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   416 AA;  44480 MW;  CCE265588BB54399 CRC64;
     MAGNLLRGPP LLLRAADKYP RTPKCARCRN HGVVSALKGH KRYCRWKDCM CAKCTLIAER
     QRVMAAQVAL RRQQAQEENE ARELQLLYGT AEGLALAAAN GIIPPRPNYE VFGSVSSESN
     SESSIPKYEL FPKSQLSSST PPQQSGGKPV SAESDSAPGI SSPDARHEGG SGSENGDSES
     FINSPVSKPL KDGEETPGSV SSLGSDSGSE IDKDEQEPSP SSVASRHMNA IDILTRVFPS
     HKRSVLELVL QGCGKDVVQA IEQILNNGGA QAPKAGAEET WTAERMLQSA QQLPAASATT
     APSSRPMLPG AMALSNRSAF SPLQPNAPHF GADPGSYPLG THLGLNPLRL AYSAHSRGLA
     FMTPYSTTGL MPTLGFRPPM DYAFSDLIRD RTMLHKEQPY ASGLYGPLVN NTPDKQ
 
 
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