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DMTA2_XENLA
ID   DMTA2_XENLA             Reviewed;         437 AA.
AC   Q2MJB4;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Doublesex- and mab-3-related transcription factor A2;
DE   AltName: Full=Doublesex- and mab-3-related transcription factor 5;
GN   Name=dmrta2; Synonyms=dmrt5;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Moers V.M., Bellefroid E.J.;
RT   "Molecular cloning and expression pattern of the Dmrt5 gene during
RT   embryonic development.";
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in sexual development.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
CC   -!- SIMILARITY: Belongs to the DMRT family. {ECO:0000305}.
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DR   EMBL; DQ329358; ABC55871.1; -; mRNA.
DR   RefSeq; NP_001089148.1; NM_001095679.1.
DR   AlphaFoldDB; Q2MJB4; -.
DR   SMR; Q2MJB4; -.
DR   GeneID; 734181; -.
DR   KEGG; xla:734181; -.
DR   CTD; 734181; -.
DR   Xenbase; XB-GENE-997967; dmrta2.S.
DR   OrthoDB; 1573364at2759; -.
DR   Proteomes; UP000186698; Chromosome 4S.
DR   Bgee; 734181; Expressed in neurula embryo and 3 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0022008; P:neurogenesis; IMP:CACAO.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 4.10.1040.10; -; 1.
DR   InterPro; IPR001275; DM_DNA-bd.
DR   InterPro; IPR036407; DM_DNA-bd_sf.
DR   InterPro; IPR005173; DMA.
DR   InterPro; IPR026607; DMRT.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR12322; PTHR12322; 1.
DR   Pfam; PF00751; DM; 1.
DR   Pfam; PF03474; DMA; 1.
DR   SMART; SM00301; DM; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF82927; SSF82927; 1.
DR   PROSITE; PS40000; DM_1; 1.
DR   PROSITE; PS50809; DM_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Zinc.
FT   CHAIN           1..437
FT                   /note="Doublesex- and mab-3-related transcription factor
FT                   A2"
FT                   /id="PRO_0000333780"
FT   DOMAIN          254..289
FT                   /note="DMA"
FT                   /evidence="ECO:0000255"
FT   DNA_BIND        49..96
FT                   /note="DM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00070"
FT   REGION          160..253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        183..209
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   437 AA;  46522 MW;  BA0766EDF1B4D150 CRC64;
     MELNGPPSSQ VPHTPTCAPS LPITVAGTLL RGPQLLLRAA EKYPRTPKCA RCRNHGVVSA
     LKGHKRYCRW KDCMCAKCTL IAERQRVMAA QVALRRQQAQ EENEARELQL LYGTAEGLAL
     AAANGILPPR PAYEVFGSLC GEGGTDSKIQ KFDLFPKSLI PRSMTPQLPS GGKPGSPDSE
     PVSGSAPGAS SPEAQPGSGS ENGDGESLLS SPISKELKEG EESPSLISPL SSESGSDAEK
     DEQDPSSSSL ARQRTPINIL TRVFPAQKRS VLELVLQGCG GDVVQAIEQI LNNRSQDKGE
     GTWSKDGALQ SIQPSVSSTH RPLIAGALTP AIGTIGSRSA FSPLQPNAAH FGTEANTYQL
     GGHIGLNPLR LAYSAHSRGL AFMAPYSTAG FMPTLGFRPP MDYAFSDLMR DRANVHKDQV
     YTNGLYGPVV NNNAEKQ
 
 
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